1 What is Nasohist-DM?

Brand: Nasohist- DM, Quartuss DM, Alka- Seltzer Plus and Cold, C- Phen DM, Cardec DM, Ceron- DM, Cerose DM, Corfen DM, DP Dec DM, Dec Chlorphen DM, Donatussin DM, Histadec DM, Maxiphen ADT, Mintuss DR, Neo DM, Nohist DMX, Norel DM, P Chlor DM, PD- Cof, Poly- Tussin DM, Reme Tussin DM, Rondec- DM, Rondex- DM, Sildec PE DM, Tri- Vent DPC, Trital DM, Tussplex DM, Zotex- 12D

Generic: Chlorpheniramine, Dextromethorphan and Phenylephrine

Nasohist-DM is a cough suppressant, anti-allergy and decongestant drug, used to treat symptoms of allergies, common cold, flu, hay fever and other breathing problems (i.e. bronchitis, sinusitis). This is a drug combination of chlorpheniramine, dextromethorphan, and phenylephrine.

Chlorpheniramine is an anti- allergy/ antihistamine drug. This decreases the level of histamine in the body during allergic reactions to relieve the symptoms such as itching, runny nose, sneezing and watery eyes.

Dextromethorphan is a cough suppressant or antitussive drug. This acts at the cough center of the brain to decrease your urge to cough. However, do not use this drug to relieve a cough from asthma, emphysema, and smoking.

Phenylephrine is a decongestant drug. This constricts/ shrinks the dilated blood vessels in the nasal passages to relieve stuffy nose or nasal congestion.


Read your medication guide and follow your doctor’s prescription at all times.

  • Take Nasohist- DM orally/ by mouth before or after meals per doctor’s prescription. Take this medication with food if you experienced stomach upset.
  • The dosage depends on your medical condition or treatment response. Do not adjust your dose without your doctor’s recommendation.
  • Do not break, chew or crush sustained- release tablet form of Nasohist- DM to prevent releasing the content of this medication all at once, which may intensify side effects.
  • Use a standard medicine cup/ spoon (not household spoon) to obtain the accurate amount for each dose if you are using the liquid preparation of this medication. Shake the bottle of this medication well before use for suspension preparation.
  • If you are taking the powder preparation, follow the product instruction for the amount of liquid that must be mixed with this medication for each dose.
  • Dissolve the powder completely and take in the mixture. Add more water to your mixing container to dissolve the remaining medication and drink it to ensure you have taken the whole dose.
  • Avoid alcohol intake and activities that require mental alertness (i.e. driving, operating machinery) because this medication can cause dizziness.
  • Avoid intake of MAO inhibitor drugs 14 days before, during and 14 days after your Nasohist- DM treatment.
  • Increase your fluid intake to prevent dryness of mouth, nose or throat.
  • Check your blood sugar on a regular basis if you are diabetic and inform you, doctor, if the results are high or low because some preparation of this medication contains sugar.
  • Continue using this medication on a regular schedule (same time of the day). Do not stop taking this medication abruptly without consulting your doctor.

Inform your doctor immediately if your condition aggravates or does not improve.

Take your missed dose as soon as possible. However, make sure that the time interval between the missed and the next dose is not too close. Otherwise, stick with the regular schedule and leave out the missed dose. Do not double dose to cover up a missed dose. Record your missed dose and inform your doctor immediately if you missed several doses.


Nasohist-DM may interact with:

  • MAO inhibitor drugs (i.e. isocarboxazid, moclobemide, phenelzine, procarbazine, selegiline)
  • Oral (taken by mouth) or topical (skin) antihistamine (i.e. diphenhydramine)
  • Antispasmodics (i.e. atropine)
  • Beta blockers (i.e. metoprolol, atenolol)
  • Parkinson’s disease medication (i.e. benztropine)
  • Guanethidine
  • Inhaled anesthetics (i.e. halothane)
  • Methyldopa
  • Reserpine
  • Scopolamine
  • Tricyclic antidepressants (i.e. amitriptyline, desipramine)
  • Another cough- and- cold products
  • Diet aids
  • Anticonvulsant/ anti- seizure drugs (i.e. carbamazepine)
  • Sleeping pills
  • Anti- anxiety drugs (i.e. alprazolam, diazepam, zolpidem)
  • Muscle relaxants
  • Narcotic pain relievers (i.e. codeine) and
  • Antipsychotic drugs (i.e. chlorpromazine, risperidone)

Some drugs may either lessen the beneficial effects or worsen the side effects of Nasohist- DM. Likewise, Nasohist- DM may make some drugs less efficient or intensify their side effects.

Make sure to inform your doctor about all other drugs you are currently taking or using (prescribed and non-prescribed medications including vitamins, minerals, and herbal products) to check for possible drug interaction with Nasohist- DM.

Never alter the doses of other medications while on Nasohist- DM neither stop nor start any medicine without the doctor’s recommendation.

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking Nasohist- DM, tell your health care provider if you have/are:

  • Any allergies to any substance, food or medication, particularly to Nasohist- DM, chlorpheniramin, dextromethorphan or phenylephrine;
  • Medical history or a present condition such as:
  • Pregnant, planning to get pregnant or currently breastfeeding a baby (Nasohist- DM can harm the unborn baby and it can pass through breast milk that may harm the nursing child. The risks and benefits of taking this medication upon pregnancy must be discussed well with your doctor.)