1 What is Nebcin?

Brand: Nebcin

Generic: Tobramycin

Nebcin injection is a type of aminoglycoside antibiotic that is used in treating serious bacterial infections in various body parts.

This drug works by preventing the growth of bacteria and killing them. It only works on bacterial infections and does not affect viral infections, such as colds and flu.

Using this drug may cause serious side effects like hearing loss, damage to your sense of balance, and may affect the kidneys, as well. These side effects are more common in newborn infants and the elderly.

2 What to Know Before Using

If you are about to start Nebcin, speak with your doctor about what you need to know. The risks and benefits the medicine offer must be weighed.

When using Nebcin, you and your doctor must consider the following:

Allergies: If you have any unusual reaction to any medicine, be sure to tell your doctor about it. Additionally, disclose other types of allergies - food, preservatives, animals, or dyes, if there are any. Read the package ingredients carefully and make sure you are not allergic to any of its ingredients.

Pediatric: Using this drug in children does not affect its usefulness and effectiveness. Nevertheless, it should be used with caution in newborn infants and premature infants.

Geriatric: Studies done in the elderly does not show geriatric-specific side effects that will limit the usefulness of this drug in the elderly. Utmost caution is required, however, since the elderly is more susceptible to unwanted side effects like kidney problems.

Pregnancy: Studies show that using tobramycin in pregnant women poses a risk to the fetus. Nonetheless, in the case of life-threatening situations, the benefits of using this drug may outweigh any potential risk.

Breastfeeding: Although there are no adequate studies in lactating mothers that determine potential risk in an infant when breastfeeding, the benefits should be weighed against the risks before taking this medication.

Drug Interactions: Some drugs have adverse effects when used together. Make sure to inform your doctor about other drugs you are taking, so that alterations and precautions will be made if necessary. Before using vinorelbine, talk to your doctor about possible interactions if you are taking other medications.

It is also important to inform your doctor if you are smoking tobacco or drinking alcohol since these may interact with the drug’s effectiveness.

Inform your doctor about any drug you are using, prescription or nonprescription, especially the following drugs:

  • Amifampridine
  • Atracurium
  • Alcuronium
  • Cidofovir
  • Colistimethate Sodium
  • Cisatracurium
  • Decamethonium
  • Doxacurium
  • Fazadinium
  • Ethacrynic Acid
  • Furosemide
  • Foscarnet
  • Gallamine
  • Hexafluorenium
  • Lysine
  • Metocurine
  • Mannitol
  • Mivacurium
  • Pipecuronium
  • Pancuronium
  • Rapacuronium
  • Succinylcholine
  • Rocuronium
  • Vecuronium
  • Tubocurarine
  • Vancomycin

Other medical problems: How you use this medicine may be affected if any other medical problems are present. If you have health issues other than the ones being treated by this drug, consult your doctor first before using this medicine.

Inform your doctor if you have asthma, sulfite allergy, extensive burns, cystic fibrosis, kidney disease, muscle problems, myasthenia gravis, nerve problems, or Parkinson’s disease.

3 Proper Usage

Proper usage of Nebcin requires strict adherence to your doctor’s orders. Nebcin is to be given only by a trained health professional such as a nurse. It is administered by injecting it into a vein or muscle.

Full treatment period is required to ensure the infection clears up completely, regardless if you are already feeling well after a few doses.

Regular schedule is important when using this medicine, as tobramycin works best when there is a constant amount of the drug in the blood.

Increase fluid intake during treatment to keep the kidneys working well and prevent kidney problems from occurring.

4 Precautions to Take

Before using Nebcin, there are some precautions you must take. Close monitoring is important while receiving this drug to make sure the drug is working properly and check if there are any unwanted effects.

Your doctor may request urine, blood and nerve tests, as well as a hearing test to see if the drug is affecting your hearing. Your doctor might also check the electrolytes in the blood.

Using tobramycin while pregnant may harm the unborn fetus. Make sure to use an effective birth control form to keep you from getting pregnant. If you think you got pregnant while using this drug, inform your doctor right away.

Using this drug may result in anaphylaxis or other serious allergic reactions. If you notice peeling, loosening or blistering of the skin, hives, itching, hoarseness, mouth sores, shortness of breath, trouble breathing and swallowing, or any swelling of the face, hands or mouth upon receiving a dose of this drug, seek emergency medical attention.

If you notice sudden hearing loss or decrease in hearing, stop use and check with your doctor immediately. Inform your doctor if there is dizziness, lightheadedness, the sensation of spinning, or constant movement of self or surrounding, inform your doctor. These symptoms may cause permanent damage to your hearing or sense of balance when left untreated.

Consult your doctor if any symptoms of a serious kidney infection are present, such as blood in urine, increased thirst, change in amount or frequency of urination, nausea, vomiting, swelling of the feet or lower legs, loss of appetite, or weakness.

5 Potential Side Effects

Make sure you meet with your doctor in using Nebcin to avoid unwanted potential side effects. However, if they do occur, immediate medical attention might be needed.

Consult your healthcare professional if any of these occur:

  • Black, tarry stools
  • Bleeding gums
  • Blood in the urine or stools
  • Cloudy urine
  • Chills
  • Clumsiness
  • Loss of heat from the body
  • Cough
  • Ringing or buzzing or other unexplained noise in the ears
  • Cracks in the skin
  • Dizziness or lightheadedness
  • Decrease in the amount of urine
  • Feeling of constant movement of self or surroundings
  • Fever
  • Feeling of fullness in the ears
  • Loss of balance
  • Ulcers, sores, or white spots in the mouth
  • Nausea
  • Shortness of breath
  • Loss or change in hearing
  • Unsteadiness
  • Pinpoint red spots on the skin
  • Pale skin
  • Scaly skin
  • Red, swollen skin
  • Sensation of spinning
  • Troubled breathing with exertion
  • Sore throat
  • Trouble in hearing
  • Unusual weakness or tiredness
  • Unusual bruising or bleeding
  • Vomiting

While most of these side effects usually diminish as the body adjusts to the drug, calling your doctor may be needed. Some patients may experience side effects not listed above. If you want to report side effects, you may do so by calling the FDA at 1-800-FDA-1088.

6 Related Clinical Trials