1 What is Neo-Fradin?

Brand: Neo-Fradin

Generic: Neomycin

Neo-Fradin is a prescription medicine used in minimizing the symptoms of a condition called hepatic coma, a liver disease complication.

Furthermore, this medicine may also be used together with other drugs to help prevent infection during bowel surgery.

2 What to Know Before Using

Your doctor will inform you of what you need to know before using Neo-Fradin. The risks and benefits the medicine offer must be weighed. Before using this medicine, you and your doctor must consider the following:


If you have any unusual reaction to any medicine, be sure to tell your doctor about it. Additionally, disclose other types of allergies - foods, preservatives, animals, or dyes, if there are any. Read the package ingredients carefully and make sure you are not allergic to any of its ingredients.


Using this drug in premature infants and neonates may possibly result in hearing damage, damage to the sense of balance, and kidney problems, because they are more sensitive to the effects of the drug.


Using this drug in the elderly may possibly result in serious side effects like hearing damage, damage to the sense of balance, and kidney problems, because they are more sensitive to the effects of the drug.


Use of this medicine is not recommended during pregnancy as studies show possible risk to developing a fetus.


While there are no specific studies done in lactating women to determine the risk of using this drug to the breastfeeding infant, you may weigh the potential benefits against the risks before using this drug.

Drug Interactions

Certain medicines have adverse effects when used together. Nevertheless, it is still possible to take other medicines when taking this drug. Make sure to inform your doctor about other drugs you are taking, so that alterations and precautions will be made if necessary.

Using this with certain medicines needs utmost caution because the combination may result in certain side effects. Before taking this drug, talk to your doctor about possible interactions if you are taking other medications, both prescription and over-the-counter, as well as vitamin and herbal supplements.

Other medical problems

Using oral neomycin may not be advised if you have certain medical conditions. Or, you may have to take extra precautions when using this drug, particularly if you have:

Talk with your doctor before using this medicine if you have any other medical conditions.

3 Proper Usage

To use Neo-Fradin properly, you must follow all instructions given by your doctor. Neo-Fradin may be taken in liquid and tablet forms. If you are taking it in liquid form, use a measuring spoon to measure the medicine accurately.


Follow your doctor’s orders on dosage. Do not adjust dosage, take it less or more frequently or stop intake without consulting your doctor.

For oral dosage form in patients in a coma resulting from a liver disease, give 1-3 grams every 6 hours for 5-6 days. The dose in children is based on body size and must be determined by the doctor. For use in cleaning the bowel before a surgical procedure, use 1 gram hourly for 4 hours, then give 1 gram every 4 hours in a 24-hour period.

Missed dose

Take the missed dose as soon as possible. In case it is almost time for the next dose, skip the missed one and follow your regular dosing schedule. Never take double doses.


Keep the medicine in an airtight container at normal room temperature. Keep it away from direct light, heat, and moisture. Do not let it freeze. Keep the medicine out of children’s reach. Throw away any outdated medicine or medicine that are not in use. Keep the medicine in its original package until needed.

4 Potential Side Effects

As with many medications, there are several potential side effects associated with Neo-Fradin. You may experience some side effects that may not need special medical attention. However, if any side effects become bothersome, check with your doctor.

5 Related Clinical Trials