Nilandron is an antiandrogen drug used with surgery for the treatment of metastatic prostate cancer in men.
This drug works by blocking the effects of testosterone, which helps stop the growth and spread of cancer cells. This drug requires a prescription.
2 What to Know Before Using
Before using Nilandron, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.
Studies in children regarding the correlation of age to the effects of nilutamide have not been performed while safety and efficacy have not been established. Data regarding the relationship of age to the effects of nilutamide in geriatric patients are still unavailable.
Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate. Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as Fosphenytoin, Phenytoin, Theophylline, or Warfarin.
Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects.
Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. Inform your doctor if you have any other medical problems such as liver disease, lung disease or other breathing problems.
To use Nilandron properly, you must follow all instructions given by your doctor. To prevent any side effects, take this drug exactly as directed on the label or as prescribed by your healthcare professional.
Take this drug on the day of or the day after your surgery. Check with your healthcare professional before you stop taking this drug. You can take this drug with food or on an empty stomach.
The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.
The dosage of this drug you take depends on the medical problem for which you are using this drug. Adults with prostate cancer are given 300 milligrams once a day for the first 30 days, then 150 mg once a day. Use and dose in children must be determined by your healthcare professional.
A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.
Store the drug in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.
Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
If you take Nilandron, your doctor should perform routine checkups and advise you in taking precautions. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood tests.
Consult with your healthcare professional if you have shortness of breath, difficulty with breathing, or chest pain while you are using this drug.
Check with your healthcare professional immediately if you experience symptoms of the liver such as clay-colored stools, dark urine, fever, headache, loss of appetite, nausea or vomiting, pain or tenderness in the upper right side of the stomach, unusual tiredness or weakness, or yellow eyes or skin.
Taking this drug with alcohol may cause unwanted effects such as feeling dizzy or lightheaded when getting up from a lying or sitting position suddenly, having flu-like symptoms, or flushing of the face.
Care must be given while driving, especially at night or when you drive into or out of tunnels, as this drug can temporarily change the way your eyes react to light.
You may not be able to see as well as usual for several minutes after going from bright light to darkness. To help reduce these effects, it is recommended to wear eyeglasses with tinted lenses.
5 Potential Side Effects
As with many medications, there are several potential side effects associated with Nilandron. Side effects may vary for each individual and prompt medical attention should be given if they occur.
Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:
Swelling of the face, fingers, feet, or lower legs
Vomiting of blood or material that looks like coffee grounds
Weight gain or loss
Some side effects may occur that usually do not need medical attention. As your body adjusts to the drug, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.
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