1 What is Nitro-Bid?

Brand: Nitro-Bid, Nitronal

Generic: Nitroglycerin

Nitro-Bid injection is a nitrate used for the treatment of hypertension during surgery or to control congestive heart failure in patients with a history of heart attack. This drug may also be used to induce hypotension during surgery.

Angina in patients who have been treated with other drugs that are ineffective can also be treated with this drug. This drug relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This drug is to be given only by or under the direct supervision of your healthcare professional.

2 What to Know Before Using

Before using Nitro-Bid, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children regarding the correlation of age to the effects of nitroglycerin injection have not been performed while safety and efficacy have not been established. Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of nitroglycerin injection.

Adjustments in the dose of the elderly may be required since they are more likely to have age-related liver, kidney, or heart problems. Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Avanafil
  • Riociguat
  • Sildenafil
  • Tadalafil
  • Vardenafil
  • Alteplase
  • Recombinant Heparin
  • Acetylcysteine
  • Aspirin
  • Dihydroergotamine
  • Pancuronium

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your doctor if you have any other medical problems such as:

3 Proper Usage

To use Nitro-Bid properly, you must follow all instructions given by your doctor. A trained healthcare professional will be the only one to give you this drug in a hospital.

This drug is administered intravenously through a needle placed in one of your veins.

4 Precautions to Take

Before using Nitro-Bid, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug.

Taking riociguat (AdempasВ®), sildenafil (ViagraВ®), tadalafil (CialisВ®), or vardenafil (LevitraВ®) with this drug is not recommended as these may cause blurred vision, dizziness, lightheadedness, or fainting.

Seek immediate medical attention if you experience an angina attack while taking these drugs. Dizziness, lightheadedness, or faintness may occur, especially when you get up quickly from a lying or sitting position.

Getting up slowly may help. This drug may cause headaches which are a sign that it is working. Consult with your healthcare professional if you have severe pain.

Inform any healthcare professional who treats you that you are using this drug as it may affect the results of some medical tests.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Nitro-Bid. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Bluish-colored lips, fingernails, or palms
  • Dark urine
  • Difficulty with breathing
  • Dizziness or lightheadedness
  • Fever, headache
  • Pale skin
  • Rapid heart rate
  • Sore throat
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness, arm, back, or jaw pain
  • Blurred vision
  • Chest pain or discomfort
  • Chest tightness or heaviness
  • Confusion
  • Dizziness
  • Faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Fainting
  • Fast or irregular heartbeat
  • Sweating, or symptoms of overdose such as blurred or loss of vision
  • Bulging soft spot on the head of an infant
  • Change in consciousness
  • Change in the ability to see colors especially blue or yellow
  • Cold
  • Clammy skin
  • Convulsions
  • Disturbed color perception
  • Double vision
  • Feeling of constant movement of self or surroundings
  • Flushed skin
  • Halos around lights
  • A severe and throbbing headache
  • Increased sweating
  • Loss of appetite
  • Loss of consciousness
  • Nausea or vomiting
  • Night blindness
  • Over bright appearance of lights
  • Paralysis
  • Sensation of spinning
  • Slow or irregular heartbeat
  • or Tunnel vision

Some side effects may occur that usually do not need medical attention. As your body adjusts to the drug, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials