1 What is Nubain?

Brand: Nubain

Generic: Nalbuphine

Nubain injection is a narcotic analgesic that is used in relieving moderate to severe pain. The drug is also administered with general anesthesia before an operation, or given before and after a minor or major surgery, as well as while giving birth to relieve pain.

Nalbuphine injection works on the CNS or central nervous system to alleviate pain. As a narcotic pain reliever, this drug may be addicting and may cause physical and mental dependence when used for a long time.

Nevertheless, people who experience chronic pain should not let the fear of addiction to this drug keep them from using it to stop their pain.

When narcotics are used for the right purpose, mental addiction is less likely to happen. If treatment is stopped abruptly, physical dependence to this drug may lead to withdrawal symptoms.

You may prevent physical dependence by reducing the dose of the medicine gradually, or as advised by your doctor. Nalbuphine is a prescription drug.

2 What to Know Before Using

If you are about to start Nubain, speak with your doctor about what you need to know. The risks and benefits the medicine offer must be weighed.

Before using Nubain, you and your doctor must consider the following:

  • Allergies: If you have any unusual reaction to any medicine, be sure to tell your doctor about it. Additionally, disclose other types of allergies - foods, preservatives, animals, or dyes, if there are any. Read the package ingredients carefully and make sure you are not allergic to any of its ingredients.
  • Pediatric: Safety and efficacy of use in pediatric patients have not been established.
  • Geriatric: No available information on the use of this drug in the elderly patients.
  • Pregnancy: There are no adequate studies done on pregnant women to determine safety and efficacy of use.
  • Breastfeeding: Use of this drug may pose minimal risk to the breastfeeding infant when used by the lactating mother.
  • Drug Interactions: Certain medicines have adverse effects when used together. Make sure to inform your doctor about other drugs you are taking, so that alterations and precautions will be made if necessary.

Before using midazolam, talk to your doctor about possible interactions if you are taking other medications. It is also important to inform your doctor if you are smoking tobacco or drinking alcohol since these may interact with the drug’s effectiveness.

If you are taking naltrexone, your doctor may decide against giving you nalbuphine.

Furthermore, using this narcotic analgesic is also not recommended if you are using:

    • Alphaprodine
    • Alfentanil
    • Buprenorphine
    • Bromazepam
    • Codeine
    • Carbinoxamine
    • Donepezil
    • Dihydrocodeine
    • Fentanyl
    • Fospropofol
    • Flibanserin
    • Hydromorphone
    • Hydrocodone
    • Levorphanol
    • Meperidine
    • Meclizine
    • Methadone
    • Morphine Sulfate
    • Morphine Liposome
    • Oxymorphone
    • Oxycodone
    • Propoxyphene
    • Suvorexant
    • Sufentanil
    • Tapentadol

Other Medical Problems: If you have other medical problems, the use of this medicine may be affected. Inform your doctor if you suffer from other medical problems, such as alcohol abuse, asthma or other breathing problems, drug dependence, brain tumor, head injuries, increased pressure in the head, bradycardia, heart attack, respiratory depression, kidney disease or liver disease.

3 Proper Usage

Proper usage of Nubain requires strict adherence to your doctor’s orders. It is placed as an injection subcutaneously, intramuscularly, or intravenously.

4 Precautions to Take

Before using Nubain, there are some precautions you must take. Close monitoring is important to allow your doctor see your progress or if the drug is working properly. Nalbuphine will aggravate the effects of other CNS depressants and alcohol.

Consult your doctor before taking antihistamines, tranquilizers, sedatives, sleeping pills, anesthetics, muscle relaxants, seizure medicines, barbiturates, and some dental anesthetics.

Nalbuphine may become addictive. Do not increase your dose if you feel the drug is not working well. Light-headedness, dizziness, or fainting may take place if you get up suddenly from a sitting or lying position.

Do not change the dosage or stop the use of this medicine suddenly without checking with your doctor first. Your doctor may advise reducing the dose gradually before completely stopping intake.

Doing this may help keep the condition from getting worse and minimize the possibility of withdrawal symptoms, like stomach or abdominal cramps, fever, anxiety, nausea, sweating, tremors, runny nose, or sleeping troubles.

5 Potential Side Effects

Make sure you meet with your doctor in using Nubain to avoid unwanted potential side effects. During the course of treatment, you will be monitored closely by your doctor to check for side effects. Most side effects will diminish as soon as the effects of the drugs wear off.