Odomzo is a Hedgehog signaling pathway inhibitor used for the treatment in adults with locally advanced basal cell carcinoma.
This drug is used in patients with skin cancer that has recurred after surgery or cannot be treated with radiation or surgery. This drug requires a prescription.
2 What to Know Before Using
If you are about to start Odomzo, speak with your doctor about what you need to know. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. Studies in children regarding the correlation of age to the effects of Odomzo have not been performed while safety and efficacy have not been established.
Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of Odomzo. Adjustments in the dose of the elderly may be required since they are more likely to have unwanted effects.
Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as:
To use Odomzo properly, you must follow all instructions given by your doctor. To prevent any side effects, take this drug exactly as directed on the label or as prescribed by your healthcare professional. This drug must be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
The capsule must be swallowed whole. Breaking, crushing, or opening the capsule is not recommended. The dose of this drug will be variable for different patients.
The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.
Adults with advanced basal cell carcinoma are given 200 milligrams once a day. Use and dose in children must be determined by your healthcare professional. A missed dose should be taken as soon as possible.
However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose. Store the drug in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
Before using Odomzo, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood and urine tests.
This drug has teratogenic potential and you will be advised to undergo a pregnancy test if you are a woman who can bear children.
It is recommended to use a highly effective form of birth control to keep from getting pregnant, as you should not become pregnant while you are taking this drug and for 20 months after stopping it.
Inform your healthcare professional immediately if you think you have become pregnant while using the drug. This drug may also cause birth defects if the father is using it when his sexual partner becomes pregnant.
It is recommended that male patients should use condoms and spermicides as forms of birth control during sexual intercourse while taking Odomzo and for 8 months after the last dose of this drug.
Donating blood or blood products is not recommended while taking this drug and for 20 months after stopping it. Donating semen is also not recommended while taking this drug and for 8 months after the last dose.
Inform your healthcare professional immediately if you develop symptoms of rhabdomylosis such as new or worsening muscle spasms, pain, or tenderness, dark urine, or decreased amount of urine while taking this drug.
Consult with your healthcare professional if you plan to have children before using this drug, as infertility has been associated with the use of this drug in women.
Check with your healthcare professional before taking any other prescription or nonprescription drugs, and herbal or vitamin supplements.
5 Potential Side Effects
As with many medications, there are several potential side effects associated with Odomzo. Side effects may vary for each individual and prompt medical attention should be given if they occur.
Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:
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