1 What is Oncovin?

Brand: Oncovin, Vincasar PFS

Generic: Vincristine

Oncovin is an antineoplastic agent used for the treatment of some kinds of cancer as well as some noncancerous conditions. This drug arrests the growth of cancer cells by interfering with their cell division.

The growth of normal body cells also may be affected by this drug. Some of these effects may be serious and must be reported to your doctor. Discuss with your healthcare professional about the risks and benefits of this drug before beginning treatment with it.

This drug is to be administered only by or under the immediate supervision of your healthcare professional. This drug requires a prescription.

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2 What to Know Before Using

Before using Oncovin, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. Studies in children have not reported any different side effects or problems than it does in adults.

More profound effects in the nervous system of the elderly are more likely to occur due to their increased sensitivity to the drug. Risks to the fetus have been reported in the animal studies but these may be outweighed by the benefits of therapy in a life threatening situation or a serious disease.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Live Boceprevir Rotavirus Vaccine
  • Live Adenovirus Vaccine Type 4
  • Live Adenovirus Vaccine Type 7
  • Amiodarone
  • Asparaginase
  • Atazanavir
  • Azithromycin
  • Live Bacillus of Calmette and Guerin Vaccine
  • Captopril
  • Carbamazepine
  • Carvedilol
  • Ceritinib
  • Clarithromycin
  • Cobicistat
  • Conivaptan
  • Crizotinib
  • Cyclosporine
  • Dabrafenib
  • Darunavir
  • Dasabuvir
  • Dexamethasone
  • Diltiazem
  • Dronedarone
  • Eliglustat
  • Erythromycin
  • Felodipine
  • Filgrastim
  • Fluconazole
  • Fosaprepitant
  • Fosphenytoin
  • Idelalisib
  • Indinavir
  • Live Influenza Virus Vaccine
  • Itraconazole
  • Ketoconazole
  • Lomitapide
  • Lopinavir
  • Live Measles Virus Vaccine
  • Live Mumps Virus Vaccine
  • Nefazodone
  • Nelfinavir
  • Nilotinib
  • Phenobarbital
  • Phenytoin
  • Piperaquine
  • Live Poliovirus Vaccine
  • Posaconazole
  • Quercetin
  • Quinidine
  • Quinupristin
  • Ranolazine
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • Live Rubella Virus Vaccine
  • Saquinavir
  • Sargramostim
  • Simeprevir
  • Smallpox Vaccine
  • St John's Wort
  • Telaprevir
  • Telithromycin
  • Ticagrelor
  • Tocophersolan
  • Tolvaptan
  • Typhoid Vaccine
  • Valspodar
  • Varicella Virus Vaccine
  • Verapamil
  • Voriconazole
  • Warfarin
  • Yellow Fever Vaccine
  • Zidovudine
  • or Nifedipine

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare professional if you have any other medical problems such as chickenpox, herpes zoster, gout, kidney stones, infection, liver disease, nerve or muscle disease.

3 Proper Usage

To use Oncovin properly, you must follow all instructions given by your doctor. This drug is given in combination with other drugs. It is important that you receive each drug at the proper time if you are using a combination of drugs.

You will be advised to increase your fluid intake in order to increase your urine output as this will help prevent kidney problems and keep your kidneys working well. Nausea and vomiting can be commonly caused by this drug.

You will be advised to continue to receive this drug, even if you begin to feel ill. Ask your health care professional for ways to lessen these effects, especially if they are severe.

The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.

4 Precautions to Take

Before using Oncovin, there are some precautions you must take. Regular visits should be made to your healthcare professional to track your progress and to monitor the effectiveness of the drug.

It is recommended to not have any immunizations during and after treatment with this drug without your healthcare professional's approval. Your body's resistance may be lowered by this drug and there is a risk that you might acquire the infection the immunization is meant to prevent.

Other persons living in your household are not recommended to take oral poliovirus vaccine, to prevent any chance of passing the poliovirus on to you. Persons who have recently taken oral poliovirus vaccine should be avoided.

Consider wearing a protective face mask that covers the nose and the mouth if exposure cannot be avoided. Tissue damage and scarring may occur if this drug accidentally seeps out of the vein into which it is injected. Inform the health care professional or nurse immediately if you notice redness, pain, or swelling at the place of injection.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Oncovin. Side effects may vary for each individual and prompt medical attention should be given if they occur. Unwanted effects can occur months or years after the drug is used.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Blood problems
  • Nervous system problems
  • Loss of hair
  • Pain or redness at place of injection
  • Black, tarry stools
  • Blood in urine or stools
  • A cough or hoarseness
  • Fever or chills
  • Pinpoint red spots on skin
  • Unusual bleeding or bruising
  • Blurred or double vision
  • Constipation
  • Difficulty in walking
  • Drooping eyelids
  • Headache
  • Jaw pain, joint pain
  • Lower back or side pain
  • Numbness or tingling in fingers and toes
  • Pain in fingers and toes
  • Pain in testicles
  • Stomach cramps
  • Swelling of feet or lower legs
  • Weakness
  • Agitation
  • Bed-wetting
  • Confusion
  • Convulsions
  • Decrease or increase in urination
  • Dizziness or lightheadedness when getting up from a lying or sitting position
  • Hallucinations
  • Lack of sweating
  • Loss of appetite
  • Mental depression
  • Painful or difficult urination
  • Trouble in sleeping
  • Unconsciousness
  • Sores in mouth and on lips.

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.