Proper usage of Otrexup requires strict adherence to your doctor’s orders. A doctor or a trained health professional will inject this medicine through a needle into your vein, skin, muscle or spine.
If you are using the injection form at home use it exactly as your doctor directed. It comes with an instruction. Read and understand it carefully. Give an injection shot in stomach or thigh muscles. Use a different body area each time you give yourself a shot.
It is different for different patients. Dosage mentioned below is an average dose. You must follow your doctor’s command.
For rheumatoid arthritis or juvenile arthritis:
Adults: The dose is usually 7.5 milligrams (mg) once per week.
Children: The dose is usually 10 mg per square meter (m(2)) of body size once per week.
Adults: The dose is 10 to 25 mg once per week. However, the dose is usually not more than 30 mg once per week.
The dose in children is determined by your doctor.
Do not miss the dose. If you forget your dose, ask your pharmacist or doctor for instructions.
Store it at room temperature. Keep it away from children.
4 Precautions to Take
In using Otrexup, you must be careful and take some precautions as advised by your doctor. Your doctor should check your daily progress at regular visits. He/she may want a blood or urine test to check for unwanted effects.
Use an effective form of birth control methods during the treatment and after 1 menstrual cycle from your last dose as Methotrexate can harm an unborn baby. Men should use birth control during and for at least 3 months after the last dose of Methotrexate.
It can result in infertility (unable to have a child).
Discuss this with your doctor, if you have any concern regarding this.
Do not drink alcohol while using Methotrexate as it may cause or aggravate liver diseases. Inform your doctor if you experience a headache, stomach pain, vomiting, dark-colored urine, loss of appetite, weight loss, general feeling of tiredness or weakness, light-colored stools, upper right stomach pain or yellow eyes or skin.
These are symptoms of organs toxicity caused by Methotrexate.
Methotrexate may cause drowsiness, dizziness, blurred vision, or light-headedness. These effects may be worse if you take it with food. Use Methotrexate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
It is a bone marrow suppressant. It temporarily reduces your white blood cells and platelets, and so making you susceptible to infections and bleeding. While using this drug you should avoid people with the infection.
Be careful when using a regular toothbrush, dental floss, or toothpick. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.
Do not have any immunization (vaccination) during and after the treatment with this drug without your doctor’s approval. Methotrexate may lower your body's resistance and there is a chance you might get the infection, the immunization is meant to prevent.
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