Pancof HC

1 What is Pancof HC?

Brand: Pancof HC, Rezira

Generic: Hydrocodone And Pseudoephedrine (Oral Route)

Pancof HC is used to relieve cough and nasal congestion (stuffy nose) which is a manifestation of the common cold.

Hydrocodone is a narcotic agent which acts as a cough suppressant. It acts in the cough center in the brain to suppress cough. Pseudoephedrine belongs to the decongestant family and decreases nasal congestion by constricting the blood vessels and limiting the flow of blood to the nasal passage.

Hydrocodone can result in physical and mental dependence when used for a long time. Dependence is the habit-forming property of a drug. If the treatment is stopped abruptly, physical dependence can lead to withdrawal effects on the body.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Liquid
  • Solution
  • Tablet
  • Syrup

2 What to know before using

If you are about to start Pancof HC, speak with your doctor about what you need to know.

The advantages of a drug should always be weighed against its associated risks. Your doctor will consider these risks before prescribing the drug and will inform you about them. Following factors should be considered before taking this drug:


If you have had an allergic reaction to this drug in the past, inform your doctor. You should also tell your healthcare provider if you are allergic to any other drugs or food products.

Age specific problems:

The data regarding the effects of this medicine specific to the pediatric age group is not yet available. Its safety and efficacy has not been established in children less than 8 years of age.

The studies specific to the geriatric age group have not been carried out, therefore its safety and efficacy have not been established in older age group.

However geriatric population is more prone to having:

  • confusion,
  • mental problems,
  • kidney, liver and heart problems.


Regarding the safety of usage of this drug during pregnancy, it comes under “C” category, which means that clinical trials on animals have revealed harmful effects to the developing fetus or relevant studies have not been performed.

Drug Interactions:

Certain drugs should not be used together because they can interact inside the body which can have a harmful effect. On the other hand certain drugs are allowed to be used together. So, you should tell your doctor about any other medications you are taking. If there is a chance of interaction between those two drugs, the doctor may change the dose or may prescribe an alternative drug. 

For a complete list of medications that may interact with Pancof HC, speak with your doctor.

Furthermore, certain medications should not be taken with alcohol or tobacco, which may also result in harmful interactions. Ask your doctor about the concurrent use of this drug along with alcohol or tobacco.

You should also inform your doctor about any other medical condition you may be suffering from, especially:

3 Proper usage

To use Pancof HC properly, you must follow all instructions given by your doctor.

Hydrocodone has a tendency to cause dependence (habit-forming). So, it is important that you only take the recommended dose. This drug should be used exactly as prescribed by your doctor in order to avoid adverse effects. Do not overuse or misuse this drug and do not use it longer than the recommended time. Read all the instructions mentioned in the medication guide.

Measure the liquid preparation accurately, using a measuring spoon. Take the medication at the same time each day. The dose of this drug varies according to the condition of each person. The number of doses per day, the time interval between the doses and the length of time you have to take the medicine depends on your condition individually and all these factors should only be determined by your healthcare provider. Follow each and every instruction of your doctor and also read the label carefully.

In case you miss one dose of this drug, take it as soon as you can. If it is almost time for your subsequent dose, you can then skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.


This medicine should be stored at room temperature within a closed container, away from heat, direct light and moisture. Keep this drug out of the reach of children. Do not store expired or outdated medicines or the medicine no longer needed.

4 Precautions to take

Before using Pancof HC, there are some precautions you must take.

Your doctor will monitor the response to this medicine and look for any side effects. Therefore, regular follow-up is necessary during and after the treatment.

Contact your doctor if your symptoms have not improved even after taking the full course of treatment.

Do not take MAO inhibitors while you are on his medication.

Hydrocodone will enhance the effects of alcohol or any other CNS depressants like benzodiazepines. So avoid taking them concurrently. Hydrocodone can cause severe constipation. It can also lead to dizziness, drowsiness and loss of attention. The overdose of hydrocodone can also cause serious symptoms and needs urgent medical help. This medicine can cause serious types of allergic reactions including anaphylaxis. It is a serious condition and needs emergency medical attention.

Avoid taking any other medicine unless thoroughly discussed with your doctor. Always ask your doctor before using any prescription, non-prescription or herbal medicine.

5 Potential side effects

If you notice any side effects of Pancof HC, immediately make an appointment with your doctor.

Every medicine has a propensity to cause unwanted effects along with its desired effects. Although these side effects may occur only in a handful of patients but if they do occur, contact your physician immediately.

This medication is associated with following side effects:

  • blurred vision
  • bloating
  • Abdominal or stomach cramps or pain
  • chest pain or discomfort
  • cold, clammy, pale skin
  • constipation
  • confusion
  • convulsions
  • difficult or troubled breathing
  • diarrhea
  • dizziness
  • fainting
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, slow, or irregular heartbeat
  • pale or blue lips, fingernails, or skin
  • irregular, fast or slow, or shallow breathing
  • shakiness in the legs, arms, hands, or feet
  • sweating
  • slow heart rate
  • trembling or shaking of the hands or feet
  • vomiting
  • unusual tiredness or weakness
  • drowsiness
  • Diarrhea
  • headache
  • feeling of warmth
  • nausea
  • relaxed and calm
  • redness of the face, neck, arms, and occasionally, upper chest
  • sudden sweating
  • sleepiness

Seek medical help instantly, if you experience any of these symptoms while on this drug.

Also contact your healthcare professional immediately, if have overdosed on this drug. If any of these side effects becomes more bothersome or does not go away, contact your doctor.