1 What is Poly-B?

Brand: Poly-B

Generic: Polymyxin B

Poly-B injection is an antibiotic used for the treatment of bacterial infections in many different parts of the body.

This drug kills bacteria by disrupting their cell membrane. This drug is ineffective against viral infections.

This drug is to be given only by or under the direct supervision of a healthcare professional.

2 What to Know Before Using

Before using Poly-B, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. Studies in children have not demonstrated any pediatric-specific problems that would limit the utility of polymyxin B injection.

Data on the correlation of age to the effects of polymyxin B injection in geriatric patients are still unavailable. Infant risk is still undetermined when using this drug during breastfeeding.

Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Alcuronium
  • Atracurium
  • Cisatracurium
  • Doxacurium
  • Fazadinium
  • Gallamine
  • Hexafluorenium
  • Metocurine
  • Mivacurium
  • Pancuronium
  • Pipecuronium
  • Rapacuronium
  • Rocuronium
  • Tubocurarine
  • Vecuronium

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects.

Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. Inform your healthcare provider for any other medical problems such as kidney disease.

3 Proper Usage

Proper usage of Poly-B requires strict adherence to your doctor’s orders. A trained healthcare professional will be the only one to give you or your child this drug. This drug is injected into a muscle, vein, or into the back.

It is recommended to increase fluid intake to increase your urine output as this will keep your kidneys working well and help prevent kidney problems.

4 Precautions to Take

Before using Poly-B, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood and urine tests.

Check with your healthcare professional if your or your child's symptoms do not improve or if they become worse within a few days. This drug may cause diarrhea which may occur 2 months or more after you stop using it.

Check with your healthcare professional before you take any drug to treat diarrhea as this may make the diarrhea worse or make it last longer.

Check with your healthcare professional immediately if you feel weak, irritable, drowsy, trouble seeing, numbness or tingling of the arms or legs, or other problems with muscle control.

Check with your healthcare professional before you take any other prescription or nonprescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Poly-B. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • dizziness
  • drowsiness
  • fever
  • headache
  • numbness or tingling in hands or feet
  • pain in the lower back or side
  • shakiness and unsteady walk
  • stiff neck
  • unsteadiness
  • trembling
  • or other problems with muscle control or coordination

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials