Prestalia

1 What is Prestalia?

Brand: Prestalia

Generic: Perindopril and Amlodipine

Prestalia is used for the treatment of hypertension. Hypertension adds to the workload of the heart and arteries which can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

The risk of strokes and heart attacks can be reduced when blood pressure is lowered. This drug combination collectively works by blocking substances and calcium in the body that causes vasoconstriction resulting to relaxation of the blood vessels and lower blood pressure.

A lower blood pressure will increase the supply of blood and oxygen to the heart. This drug requires a prescription.

2 What to Know Before Using

Before using Prestalia, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children regarding the correlation of age to the effects of perindopril and amlodipine combination have not been performed while safety and efficacy have not been established. Data on the relationship of age to the effects of perindopril and amlodipine combination in geriatric patients are still unavailable. This drug is not recommended for use in the elderly.

Risks to the fetus have been reported in studies of pregnant women but these may be outweighed by the benefits of therapy in a life threatening situation or a serious disease. Infant risk is still undetermined when taking this drug during breastfeeding. Discuss with your healthcare professional about the risks and benefits of this drug before breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other:

  • Aliskiren
  • Sacubitril
  • Alteplase
  • Amiloride
  • Amiodarone
  • Atazanavir
  • Azathioprine
  • Azilsartan
  • Azilsartan
  • Medoxomil
  • Candesartan
  • Cilexetil
  • Canrenoate
  • Ceritinib
  • Clarithromycin
  • Clopidogrel
  • Conivaptan
  • Cyclosporine
  • Dabrafenib
  • Dantrolene
  • Domperidone
  • Droperidol
  • Eliglustat
  • Eplerenone
  • Eprosartan
  • Everolimus
  • Fentanyl
  • Idelalisib
  • Irbesartan
  • Lacosamide
  • Lithium
  • Losartan
  • Mercaptopurine
  • Nilotinib
  • Olmesartan
  • Medoxomil
  • Piperaquine
  • Potassium
  • Simvastatin
  • Sirolimus
  • Spironolactone
  • Tacrolimus
  • Tegafur
  • Telaprevir
  • Telmisartan
  • Triamterene
  • Trimethoprim
  • Valsartan
  • Aceclofenac
  • Acemetacin
  • Amtolmetin Guacil
  • Azosemide
  • Bemetizide
  • Bendroflumethiazide
  • Benzthiazide
  • Bromfenac
  • Bufexamac
  • Bumetanide
  • Bupivacaine
  • Bupivacaine Liposome
  • Buthiazide
  • Capsaicin
  • Celecoxib
  • Chlorothiazide
  • Chlorthalidone
  • Choline Salicylate
  • Clonixin
  • Clopamide
  • Cyclopenthiazide
  • Cyclothiazide
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dipyrone
  • Droxicam
  • Ethacrynic Acid
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Furosemide
  • Gold Sodium Thiomalate
  • Hydrochlorothiazide
  • Hydroflumethiazide
  • Ibuprofen
  • Indapamide
  • Indinavir
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Methyclothiazide
  • Metolazone
  • Morniflumate
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Nesiritide
  • Niflumic Acid
  • Nimesulide
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Phenylbutazone
  • Piketoprofen
  • Piretanide
  • Piroxicam
  • Polythiazide
  • Proglumetacin
  • Propionic Acid
  • Propyphenazone
  • Proquazone
  • Quinethazone
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • Sulindac
  • Tenoxicam
  • Tiaprofenic Acid
  • Tolfenamic Acid
  • Tolmetin
  • Torsemide
  • Trichlormethiazide
  • Valdecoxib
  • or Xipamide

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as:

3 Proper Usage

To use Prestalia properly, you must follow all instructions given by your doctor. The treatment of hypertension may include weight control and changes in the types of foods you eat, especially foods high in sodium. Consult with your healthcare professional before changing your diet.

Compliance with your drugs and regular checkups are important to control your hypertension. You may have to do this for the rest of your life, since it can cause serious problems, such as:

Adults with hypertension are initially given one tablet containing perindopril 3.5 milligrams and amlodipine 2.5 mg once a day. Your healthcare professional may adjust your dose if necessary.

The dose of perindopril and amlodipine must not exceed 14 mg 10 mg per day, respectively. Use and dose in children must be determined by your healthcare professional.

A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

4 Precautions to Take

Before using Prestalia, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood and urine tests.

This drug has teratogenic potential and it is recommended to use an effective form of birth control to keep from getting pregnant. Inform your healthcare professional immediately if you think you have become pregnant while using this drug.

Seek immediate medical attention if you have symptoms of anaphylaxis such as:

  • Rash
  • Itching
  • Hoarseness
  • Trouble breathing
  • Trouble swallowing
  • or Any swelling of your hands, face, lips, tongue, or throat while you are using this drug

Check with your healthcare professional immediately if you have symptoms of intestinal angioedema such as severe stomach pain. Patients with the severe cardiovascular disease may experience angina or a heart attack while taking this drug.

Check with your healthcare professional immediately if you are having:

You may experience dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position or if you have been taking a diuretic. Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous.

It is recommended to lie down so you do not faint if you feel dizzy. Then sit for a few moments before standing to prevent the dizziness from returning. Notify the health care professional or dentist in charge that you are taking this drug before having any type of surgery or emergency treatment.

Check with your healthcare professional immediately if you have symptoms of hyperkalemia such as:

  • Abdominal or stomach pain
  • Confusion
  • Difficulty with breathing
  • Irregular heartbeat
  • Nausea or vomiting
  • Nervousness
  • Numbness or tingling in the hands, feet, or lips
  • Shortness of breath
  • or Weakness or heaviness of the legs

Ask your healthcare professional before you use any drug, supplement, or salt substitute that contains potassium. Consult with your healthcare professional before taking any other prescription or nonprescription drugs for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Prestalia. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • Rapid weight gain
  • Tingling of the hands or feet
  • Unusual weight gains or loss
  • Abdominal or stomach pain
  • Arm, back, or jaw pain
  • Bloody urine
  • Blurred vision
  • Chest pain or discomfort
  • Chest tightness or heaviness
  • Confusion
  • Decreased frequency or amount of urine
  • Difficult breathing
  • Dizziness
  • Faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Fast or irregular heartbeat
  • Increased thirst
  • Irregular heartbeat
  • Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • Loss of appetite
  • Lower back or side pain
  • Nausea or vomiting
  • Nervousness
  • Numbness or tingling in the hands, feet, or lips
  • Pain or discomfort in the arms, jaw, back or neck
  • Sweating
  • Unusual tiredness or weakness
  • Weakness or heaviness of the legs

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

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