Proglycem

1 What is Proglycem?

Brand: Proglycem

Generic: Diazoxide

Proglycem is a potassium channel activator used for the management of symptoms of hypoglycemia secondary to pancreatic cancer, surgery, or other conditions.

This drug works by preventing the secretion of insulin from the pancreas. This drug requires a prescription.

2 What to Know Before Using

Before using Proglycem, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children have not demonstrated any pediatric-specific problems that would limit the utility of diazoxide. Data on the relationship of age to the effects of diazoxide in geriatric patients are still unavailable.

Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate. Infant risk is still undetermined when using this drug during breastfeeding.

Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as Amphetamine, Arsenic Trioxide, Dofetilide, Fosphenytoin, Phenytoin, or Trichlormethiazide.

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as bilirubinemia, Cataracts, Congestive heart failure, Fluid retention, Gout, Pulmonary hypertension, Hypoglycemia, or Kidney diseases.

3 Proper Usage

To use Proglycem properly, you must follow all instructions given by your doctor. Take this drug exactly as directed on the label or as prescribed by your healthcare professional. The dose of this drug will be variable for different patients.

The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.

The dose in adults and children with low blood sugar is based on body weight and must be determined by your healthcare professional. The starting dose is usually 3 to 8 milligram per kilogram of body weight, divided into two or three doses, taken every 8 to 12 hours.

Your healthcare professional may increase your dose as needed and tolerated. The dose in newborn babies and infants is based on body weight and must be determined by your healthcare professional.

The starting dose is usually 8 to 15 mg per kg of body weight, divided into two or three doses, taken every 8 to 12 hours. Your healthcare professional may increase your dose as needed and tolerated.

A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the drug in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

4 Precautions to Take

Before using Proglycem, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood and urine tests. Inform the

Inform the health care professional or dentist in charge that you are using this drug before you have any kind of medical tests, surgery, dental treatment, or emergency treatment.

Consult with your healthcare professional if you have symptoms of hyperglycemia secondary to a fever or infection such as:

  • blurred vision
  • drowsiness
  • dry mouth
  • flushed and dry skin
  • a fruit-like breath odor
  • increased frequency and amount of urination
  • ketones in the urine
  • loss of appetite
  • nausea or vomiting
  • rapid and deep breathing
  • tiredness
  • unusual thirst

Check with your healthcare professional before you take any other prescription or nonprescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Proglycem. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • chest pain
  • abdominal or stomach pain
  • black, tarry stools
  • blood in the urine
  • bloody nose
  • blurred vision
  • confusion
  • dizziness
  • faintness or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • extreme thirst
  • fast, irregular, pounding or racing heartbeat or pulse
  • fever
  • flushed, dry skin
  • fruit-like breath odor
  • heavier menstrual periods
  • increased hunger
  • increased thirst
  • increased urination
  • loss of consciousness
  • nausea
  • pinpoint red spots on the skin
  • seizures
  • skin rash
  • stomachache
  • sweating
  • troubled breathing
  • unexplained weight loss
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • urinating large amounts or urinating very little
  • vomiting
  • weakness

Some side effects may occur that usually do not need medical attention. As your body adjusts to the drug, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

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