Revatio Oral is a prescription-only medicine used by men to treat erectile dysfunction (sexual impotence). It can also be used in both men and women with pulmonary arterial hypertension (increased blood pressure in the right portion of the heart and in the arteries supplying to the lungs).
Erectile dysfunction occurs when a man becomes unable to get or maintain an erection. Cenforce 100 Sildenafil works by preventing the action of an enzyme called phosphodiesterase type-5 and consequently increasing blood flow to the penis.
Therefore, sildenafil and other similar drugs are collectively called phosphodiesterase 5 (PDE5) inhibitors. Remember that without stimulation, sildenafil cannot cause an erection.
To reduce the pulmonary arterial hypertension, sildenafil inhibits the PDE5 enzyme in the lungs and dilates the blood vessels there.
Consequently, the blood flow to the lungs is increased and stress on your heart is reduced. It is available as:
- Powder for Suspension
- Tablet
Before using Revatio oral, you must know all about the risks and complications associated with it. Together with your doctor, you can decide whether the medication will do you more goods than the harms.
Here are some factors to be considered before deciding to use this medicine:
Allergies
Inform your doctor about the allergies you have, such as to this medication, other medications, or to foods, dyes, or preservatives.
Pediatric
In general, sildenafil is not used in children.
Geriatric
It may be used in elderly after adjusting the doses.
Pregnancy
It is generally safe for use in pregnancy.
Breastfeeding
It may be used in a nursing mother after assessing risks and benefits of the use.
Drug Interactions
Taking two medicines together can be harmful due to possible interactions. In other cases, even if there is a possible interaction between two medicines your doctor may advise you to take them together after adjusting the dose or issuing precautions. Here is a list of the medicines which in general are not recommended to be used with sildenafil.
Inform your doctor if you are using any of these medicines:
- Amprenavir
- Amyl Nitrite
- Boceprevir
- Cobicistat
- Darunavir
- Erythrityl Tetranitrate
- Fosamprenavir
- Isosorbide Dinitrate
- Isosorbide Mononitrate
- Lopinavir
- Molsidomine
- Nelfinavir
- Nitroglycerin
- Nitroprusside
- Pentaerythritol Tetranitrate
- Riociguat
- Telaprevir
Though usually not recommended, your doctor may decide, after adjusting dose or frequency of one or both medicines, to use this medicine with any of the following medicines:
- Ceritinib
- Clarithromycin
- Dabrafenib
- Dihydrocodeine
- Fluconazole
- Idelalisib
- Itraconazole
- Lumacaftor
- Nefazodone
- Nilotinib
- Piperaquine
- Simeprevir
- Telithromycin
- Voriconazole
Rarely and only when absolutely needed, this medicine may be used with the following medicines even if using them together may put you at risk of certain side effects. In such cases, you may have to take the adjusted dose or change the frequency of intake.
- Alfuzosin
- Bosentan
- Bunazosin
- Ciprofloxacin
- Delavirdine
- Doxazosin
- Erythromycin
- Etravirine
- Ketoconazole
- Moxisylyte
- Nebivolol
- Prazosin
- Rifapentine
- Silodosin
- Tamsulosin
- Terazosin
Other Interactions
Taking your medicine together with certain foods or items such as alcohol or tobacco may cause undesirable interactions. Talk to your doctor to know if using this medicine with food, alcohol, or tobacco is safe. DO NOT take sildenafil with the following:
- Grapefruit Juice
- Pomelo Juice
Medical Problems
Certain medical conditions might influence the effects (both positive and adverse) and action of sildenafil.
Inform your doctor about the following conditions, if any:
- Structural or birth defects of penis such as curved penis: Use cautiously.
- Unstable angina
- Recent arrhythmia (abnormal heart rhythms)
- Blood vessel diseases such as aortic stenosis
- Recent heart attack
- Heart failure
- High or low blood pressure
- Problems of retina
- Retinitis pigmentosa (an inherited disorder of the eye)
- Other eye disorders
- Recent stroke: Do not use sildenafil.
- Adults above 50
- Coronary artery disease
- Diabetes
- Heart disease
- Hyperlipidemia (high blood level of fats)
- History of eye disorders causing damages to optic nerves such as Non-arteritic anterior ischemic optic neuropathy (NAION)
- Smoking: May increase risk of NAION.
- Blood clotting problems in the past
- Current or past stomach ulcer: Safety not established.
- Severe kidney or liver problems: Use cautiously.
- Blood cancers such as leukemia and multiple myeloma
- Sickle-cell anemia (abnormal red blood cells): Use cautiously.
- Pulmonary veno-occlusive disease or PVOD (a lung disorder): Use cautiously.
To use Revatio oral properly, you must follow all instructions given by your doctor. Here are some points to consider:
- Follow your doctor’s instructions about the use of any medicine.
- Read the package insert carefully and follow accordingly. For any query, consult your doctor.
- You may also use an oral liquid form of sildenafil. Shake well before use and measure the dose accurately by using oral syringe supplied with the medicine.
- For erectile dysfunction, taking this medicine 60 minutes before intercourse is the best. However, its effect lasts up to 2 hours.
Dosing
For best results, follow your doctor to know what amount of medicine you should take in a single dose. The doses of a medicine can differ according to the conditions for which it is being prescribed. Remember your doses can differ. Consult your doctor if you have anything to ask. The doses to:
Treat erectile dysfunction (tablets)
- Adults below 65 years: Single dose of 50 milligrams (mg) once a day, 1 hour before sex.
- Adults 65 years and above: Single dose of 25 mg once a day, 1 hour before sex.
The doses may be adjusted then after.
To treat pulmonary arterial hypertension: (suspension or tablets)
- Adults: 5 or 20 milligrams (mg) 3 times a day. Maintain a gap of 4 to 6 hours between two doses.
- Children: Your doctor will decide the use and dose.
Storage
- Store in a closed container at room temperature.
- Keep away from heat, moisture, and direct light.
- Do not freeze.
- Keep away from children.
- Discard any unused or expired medicines. Discard unused oral liquid after 60 days.
As with many medications, there are several potential side effects associated with Revatio oral.
Consult your doctor immediately if you experience any of the following side effects:
Less common:
- Bladder pain
- Chest or abdominal discomfort
- Numbness, pinpricks or tingling sensations
- Blood in urine
- Painful urination
- Increased urinary frequency
- Dizziness
Rare:
- Vision problems
- Anxiety
- Feeling drunk
- Bleeding in the eye
- Chest pain chills
- Confusion
- Seizures
- Cold and pale skin
- Hearing impairment
- Decreased urine volume or frequency of urination
- Dizziness
- Fainting
- Rapid irregular heart rhythms
- Fever or chills
- Severe continuous headache
- Dilatation of the pupil
- Severe or continuous nausea
- Swollen joints
- Painful and longer erection
- Agitation
- Increased light sensitivity
- Hives
- Speech problems
- Breathing problems
- Excessive muscle contractions
- Excessive tiredness
- Transient loss of vision
Incidence not known: Blindness
Mild and non-serious side effects usually go away on their own without requiring medical intervention. You may also ask your doctor to learn more about how you may prevent or reduce the side effects.
Talk to your doctor if the side effects persist or worry you, including:
More common:
- Muscle aches
- Nosebleeds
- Breathing difficulties
- Diarrhea
- Headache
- Tender areas around the eyes and cheekbones
- Red skin
- Sneezing
- Upset stomach
- Nasal congestion
- Sleep problems
- Abnormally warm skin
Rare:
- Abdominal pain
- Nightmares
- Anxiety
- Balance problems
- Cough
- Severe or continuous diarrhea or abdominal cramps
- Swallowing difficulties
- Earache
- Increased salivation
- Abnormally sensitive skin
- Coordination problems
- Bladder incontinence
- Depression
- Numbness or tingling sensations in the hands, legs, or feet
- Hearing abnormal sounds like ringing
- Spinning sensations
- Loss of ability to feel a sexual orgasm
- Drowsiness
- Shaking
- Nausea and vomiting
The side effects of the medicine are not limited to the ones listed above. Call your doctor immediately if you experience any side effects that are uncommon or worry you. To report side effects to the FDA, contact at 1-800-FDA-1088.
