Savaysa is medicine that is used to prevent stroke and blood clots in patients with a certain heart rhythm problem such as nonvalvular atrial fibrillation. Edoxaban is also used to treat deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots may travel to the lungs and may get lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism.
This medicine is used in patients who have been treated with an injectable blood thinner for 5 to 10 days. Edoxaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps prevent harmful clots from forming in the blood vessels. This medicine is available only with your doctor's prescription.
2 What to Know Before Using
If you are about to start Savaysa, speak with your doctor about what you need to know. In case of allergies, inform your doctor if you have any unusual or allergic reactions to this medicine or to other medicines. In case of other form of allergies to foods, dyes, preservatives or animals, please, inform your medical doctor. When using non-prescription products, read the labels or products package carefully.
As for pediatric population, many appropriate studies have not been performed on the relationship of age to the effects of edoxaban in the pediatric population. Similarly, safety and efficacy studies have not been performed. As for the elderly patients, appropriate studies performed to date have not been able to show the geriatric specific problems that may limit the usefulness of edoxaban in the elderly patients.
Pregnancy information about edoxaban oral route has shown an adverse effect and there are no adequate studies in pregnant women or animal studies that have been conducted. There are also no adequate studies in pregnant women. Breastfeeding studies in women for establishing the risk of the infants when using this medication during breastfeedings. The potential benefits to the potential good will for use of the medicines are relevant.
A decision has to be made on how the medicines can be used. Drug interactions also need to be evaluated. It is known that certain medicines may not be used together at all. In other cases, two different medicines may also be used together even if interactions might occur. In this case, the doctor may change the dose or other precautions which may be necessary.
When using these medicines, it is important that your healthcare professional know if you are taking any of the medicines that are listed below. The medicines are listed on the basis of their potential significance and are not necessarily inclusive. Using of these medicines may also not be recommended, though required in some cases. If both of the medicines are prescribed together, your doctor may change the dose or how often one can use one or both of the medicines. The medicines include:
Other Interactions Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Use is not recommended in patients with these conditions:
Bleeding. This medicine need not be used in patients with this condition. Bleeding problems, history of or catheter insertion in the spine or Surgery (eg, spine), recent or history of surgery, use this medicines with caution. The risk of bleeding may be increased.
Kidney disease, moderate: Use this medicine with caution. The effects may be increased because of slower removal of the medicine from the body.
Savaysa must be used only as instructed by your medical doctor. Never take more or less of the medicine. Similarly, do not take the medicine more often than it is required. In addition, do not use too much of the medicine. It may become a habit forming or causing more of mental or physical dependence. The medicine needs to come with the medication guide.
It is important to read and follow the instructions of the medicines carefully. Ask your doctor if you have any of the questions. Take the medicine only before going to bed and or during times when it is recommended. When the supply of your medicines gets low, contact your pharmacist ahead of time.
Never allow yourself to run out of this medicine. Ensure that the medicine comes with a medication guide for your use. It is important that your read and understand this information. It is also necessary to ask your doctor if you have any questions. The medicine can also be used with or without food. In case one has any other form of medicine that has thinning potential of blood such as:
Proper medical instructions will be required on how the medicine can be best switched to edoxaban. It is recommended that the doctors will be required to follow the instructions and ask your doctors if you have any of the questions. As for the dosing, the dose of these medicines will be different for the different patients. Follow the doctor’s orders or the directions on the label. In case your dose is different, never change the dose unless your doctor tells you to do so.
Similarly, the amount of the medicine that ones take depending on the strength of the medicines. The number of doses you take relies on the strength of the medicines. Moreover, the number of doses you take everyday, time allowed between doses, and length of time you take the medicine relies on the problems for which one will be using the medicines. As for the oral dosage in the form of tablets: the prevention of stroke and blood clots in patient’s with non valvular atrial fibrillations.
Moreover, adults are required to sue a dose of 60 milligrams (mg) per day. Children’s use of the medicines and dose is determined by the medical doctor. In the treatment of the deep and venous thrombosis and pulmonary embolism. Adults will also consume about 60 milligrams (mg) one a day. Use and dose of the medicines by the children is determined by the medical doctor. In case of missed doses, the medicines must be taken as soon as possible.
But when it is almost time for the next dose, it is advisable to skip the missed doses and go back to the regular dosing schedule. Never take double doses. Store the medicine in a closed container at room temperature, away from too much heat, moisture, and direct light. In addition, keep the medicine out of reach of children. Never store outdated medicine. Dispose any of the medicines that you do not use.
4 Precautions to Take
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to make a decision on whether one should continue to take the medicines. Blood and urine tests can also be done so as to screen for the unwanted effects of the medicine when consumed.
Moreover, ensure that all doctors that treat you have information that you are using this medicine for several days before you can have any form of surgery such as dental surgery. Never stop suddenly from using this medicine without informing your doctor. One is at risk of developing stroke after you stop using this medicine.
In case of any unusual bleeding, or bruising, black tarry stools or blood in the urine or stool, headache, dizziness, weakness, pain, swelling, discomfort in a joint, pin point red spots on your skin, unusual nosebleeds, unusual vaginal bleeding that is heavier than normal; check with your doctor immediately. This may be signs of bleeding problems.
These medicines may increase the risk of blood clots in the spine or epidural area. This may lead to a long term or permanent paralysis. This is more likely to occur if you have an epidural catheter placed in your back and you are using NSAID or blood clotting medicine. Moreover, history of repeated epidural punctures or problems with your spine.
Inform your doctor right away if you have back pain, loss of bladder or bowel control, tingling, numbness, muscle weakness, especially in your legs and feet. Do not use other medicines unless they have been discussed with your doctor. This medicines also includes prescriptions or non-prescriptions available as over the counter medicines, herbal and vitamin supplements.
5 Potential Side Effects
Despite the fact that not all the side effects may occur when using Savaysa, when they occur, they may need medical attention. Always check with your medical doctor immediately if any of the following side effects occur.
Burning, Crawling, Itching, Numbness, Prickling, "Pins and Needles", or Tingling feelings
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them less common side effects includes development of rash. Other side effects that are not listed may also occur in some patients. In case of any other effect, check with your medical doctor. Call your medical doctor for medical advice about the side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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