1 What is Sivextro?

Brand: Sivextro

Generic: Tedizolid (Intravenous Route)

Sivextro (Tedizolid) is used to treat bacterial skin and skin structure infections. Tedizolid belongs to the family of medicines called antibiotics. It works by killing bacteria and preventing their growth.

Doctors often use Sivextro to treat methicillin-resistant Staphylococcus (MRSA) infections. MRSA infections tend to resist many antibacterials. Sivextro is only used for infections proven or highly suspected to be caused by MRSA. Do not use Sivextro without doctor’s supervision.

Sivextro only works for infections caused by bacteria like MRSA, and it will not work for infections caused by fungi or virus.

This form of Sivextro is an injectable drug. You need to have a prescription to purchase Sivextro. 

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2 What to Know Before Using

Before using Sivextro, you and the doctor may consider the following first.


You cannot take Sivextro if you are allergic to it.

Health conditions

Tell all of your health conditions before taking Sivextro. Sivextro must be used with precaution in patients with low white blood cell counts (neutropenia). Make sure to let the doctor know if you have a fever, flu, colds, cough, or a sore throat.


Tell the doctor if you are pregnant before using Sivextro. Sivextro is an FDA pregnancy category C drug, which means it can cause harm to the unborn baby when given to pregnant patients.


Sivextro can be passed on the breastmilk, so you must not breastfeed while using the drug.

Children and elderly

Sivextro cannot be given to patients younger than 18 years of age. There is no sufficient information on whether Sivextro cause increased risk in elderly patients. 

3 Proper Usage

This form of Sivextro is administered by injecting into the veins (intravenous route). The doctor will determine your dose of Sivextro, and you have to receive it in the hospital or doctor’s clinic.

Sivextro is usually infused once a day for 6 days. The doctor or other health providers will prepare and administer Sivextro.

It is very important to use and finish the whole course of Sivextro to treat MRSA infection. Continue to take Sivextro as prescribed even if you already feel better.

As Sivextro will be administered by health professionals and it is given in a medical facility, overdosing or missing a dose is unlikely. 

4 Precautions to Take

Do not discontinue taking or miss any doses of Sivextro without doctor’s instruction. Doing so can make MRSA much more difficult to treat.

Sivextro vials for injection is single-use only, which means it has to be disposed of once opened. Do not reuse them.

Antibiotics including Sivextro may cause diarrhea, which can be a sign of new infection. If you experienced diarrhea or other symptoms while on Sivextro, call your doctor at once.

5 Potential Side Effects

Sivextro may cause the following serious side effects:

  • Severe allergic reaction symptom such as difficulty breathing, hives, skin rash, swelling of the tongue, throat, nose, or throat.
  • Frequent diarrhea, especially if watery or bloody
  • Vision problems
  • Severe headache
  • Pain behind the eyes
  • Numbness or tingling sensation in the hands or feet

Sivextro may cause minor side effects such as: