Sivextro (Oral)

1 What is Sivextro (Oral)?

Brand: Sivextro

Generic: Tedizolid

Sivextro (oral) is an antibiotic used to treat serious infections caused by methicillin-resistant Staphylococcus aureus (MRSA). MRSA is a bacteria that that is difficult to treat because it resists almost all conventional antibiotics used in most healthcare facilities. Sivextro (Tedizolid) is one of the few medicines approved to treat MRSA infections.

This formulation of Sivextro is available in oral tablets.

Sivextro is a prescription drug and must be used only according to doctor’s instructions. 

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2 What to Know Before Using

The following must be considered before you take Sivextro tablets.


If you have allergies to Sivextro, mention it to your doctor. You could not take Sivextro tablets if you experienced allergies to Sivextro before.

Health conditions

Sivextro is known to be less effective if you have very low white blood cell counts. If you have colds, flu, cough, sore throat, or a fever, mention it to your doctor before taking Sivextro.

Use on children

Do not give Sivextro to patients younger than 18 years old.

Use on elderly

There is not much information on the additional harm caused by Sivextro to patients older than 65 years of age. Follow doctor’s instructions in giving Sivextro to elderly patients.


If you are pregnant, call your doctor first before taking Sivextro. Sivextro may be harmful to pregnant patients.


If you are breastfeeding, call the doctor first before taking Sivextro. Sivextro may be expressed in breastmilk, so do not breastmilk while taking the drug. 

3 Proper Usage

Make sure to follow doctor’s prescription in taking Sivextro tablets. Follow the doctor’s prescribed dosage, and do not take more or less of it.

You can take Sivextro tablets with or without food. Sivextro tablets are usually taken once a day for 6 days only.

Make sure not to miss any doses of Sivextro, as you will only take it once a day for less than a week. If you miss a dose of Sivextro, callthe doctor right away.

You could overdose on Sivextro if you took too many tablets. If this happens, call emergency medical services right away.

Keep Sivextro at room temperature away from heat and light.

4 Precautions to Take

It is very important to complete treatment with Sivextro. Reducing dosage or discontinuing use of Sivextro can allow the MRSA to become resistant, and it becomes harder to treat. Continue to take Sivextro as prescribed even if you are feeling well.

Sivextro may cause serious diarrhea, which can be a symptom of new infection. If this occurs, call the doctor at once.

5 Potential Side Effects

Sivextro can cause serious side effects. Call the doctor if you have any of the following:

  • Serious allergic reaction symptoms such as difficulty breathing, hives, skin rash, swelling of the nose, throat, lips, or tongue.
  • Bloody or watery diarrhea
  • Changes in vision with a severe headache or pain behind the eyes
  • Numbness or tingling sensation in the hands or feet


Sivextro may cause minor side effects such as: