Sodium Phosphate P 32

1 What is Sodium Phosphate P 32?

Sodium Phosphate P 32 is a radioactive drug or a substance that emits radiation, used by doctors as a radiation source for treatment of certain cancers.

Sodium Phosphate P 32 is a form of phosphate, which is readily absorbed by the bones. Thus, doctors often use it to treat cancers in the bone and bone marrow. Sodium Phosphate P 32 is used to treat polycythemia vera, chronic myelocytic leukemia, and chronic lymphocytic leukemia. Sodium Phosphate P 32 is also used as palliative treatment for cancers that affect the bones.

Sodium Phosphate P 32 is an injectable drug.

Sodium Phosphate P 32 requires a prescription and must be used only with doctor’s supervision. Improper use of Sodium Phosphate P 32 can result in life-threatening side effects. Because it emits radiation, Sodium Phosphate P 32 is a hazardous substance and must be prepared and handled only by trained and certified health professionals. 

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2 What to know before using

The doctor will have to consider the following first before giving treatment with Sodium Phosphate P 32.

Medical conditions

Radiation treatment is a significant and complicated procedure. Make sure to mention all your health conditions to your doctor before having treatment with Sodium Phosphate P 32.


Tellyour doctor if you have allergies to Sodium Phosphate P 32 or to sodium phosphates in foods. You cannot use Sodium Phosphate P 32 if you are allergic to it.

Use on children

Sodium Phosphate P 32 should not be used on children or patients below 18 years old.

Use on elderly patients

Elderly patients may be more sensitive to the effects of radiation, so they require closer monitoring when given treatment with Sodium Phosphate P 32. They are usually given smaller doses at longer intervals.


Sodium Phosphate P 32 should not be used on pregnant patients. Sodium Phosphate P 32 is radioactive and may cause birth defects on the unborn baby. The doctor may require a negative pregnancy test result first before giving Sodium Phosphate P 32 to female patients of reproductive age.


You should not breastfeed a child when you are taking Sodium Phosphate P 32. Sodium Phosphate P 32 can be expressed in breastmilk and can harm the nursing child.

Drug interactions

Sodium Phosphate P 32 acts on the bone marrow and can enhance the action of drugs that also reduce the activity of the bone marrow. Tell the doctor if you are taking any of the following medicines that may interact with Sodium Phosphate P 32:

  • Abacavir, Lamuvudine, and Zidovudine
  • Aldesleukin
  • Altretamine
  • Amphotericin B, systemic
  • Amphotericin B cholesteryl complex
  • Amphotericin B lipid complex
  • Amphotericin B liposomal complex
  • Anastrazole
  • Azathioprine
  • Bexarotene
  • Busulfan
  • Capecitabine
  • Carboplatin
  • Carmustine, systemic
  • Chlorambucil
  • Chloramphenicol
  • Clozapine
  • Cisplatin
  • Cladribine
  • Colchicine
  • Cyclophosphamide
  • Cytarabine
  • Dacarbazine
  • Dactinomycin
  • Daunorubicin
  • Daunorubicin, liposomal
  • Didanosine
  • Docetaxel
  • Doxorubicin
  • Doxorubicin, liposomal
  • Eflornithine
  • Epirubicin
  • Etoposide
  • Floxuridine
  • Flucytosine
  • Fludarabine
  • Fluorouracil, systemic
  • Ganciclovir
  • Gemcitabine
  • Gemtuzumab Ozogamicin
  • Hydroxyurea
  • Idarubicin
  • Ifosfamide
  • Imatinib
  • Interferon, gamma
  • Interferons, alpha
  • Irinotecan
  • Lomustine
  • Mechlorethamine, systemic
  • Melphalan
  • Mercaptopurine
  • Methotrexate
  • Mitomycin
  • Mitoxantrone
  • Paclitaxel
  • Pegaspargase
  • Pentostatin
  • Plicamycin
  • Procarbazine
  • Sodium iodide I 131
  • Sodium phosphate P 32
  • Strontium 89 chloride
  • Streptozocin
  • Temozolomide
  • Teniposide
  • Thioguanine
  • Thiotepa
  • Topotecan
  • Trimetrexate
  • Uracil mustard
  • Valganciclovir
  • Valrubicin
  • Vidarabine, systemic (with high doses)
  • Vinblastine
  • Vincristine
  • Vinorelbine
  • Zidovudine
  • Zidovudine and Lamivudine
  • Zoledronic Acid

3 Proper usage

Sodium Phosphate P 32 is prepared and administered only by doctors or health professionals with adequate training and certification in radiation oncology (a field specializing in the treatment of cancers with radiation). You can only have treatment with Sodium Phosphate P 32 in the hospital or doctor’s clinic.

Treatment course with Sodium Phosphate P 32 is different according to the patient’s disease and condition. For polycythemia vera, Sodium Phosphate P 32 is usually given every 12 weeks as needed. For chronic leukemia, a single dose of Sodium Phosphate P 32 may be given. For bone cancers, Sodium Phosphate P 32 may be given two or three times a week. The measure of radiation (in megabecquerels) also depends on the patient's condition.

Because Sodium Phosphate P 32 will be given by health professionals in a medical facility, missing a dose and overdosage is unlikely. 

4 Precautions to Take

You need to be regularly seen by the doctor and have frequent lab tests while taking Sodium Phosphate P 32. Blood counts are particularly important to determine the effects and early signs of side effects of Sodium Phosphate P 32. Make sure not to miss any clinic appointments and lab tests.

Maintain open communication with your octor and make sure to report any untoward symptoms right away.

If you are having treatment with Sodium Phosphate P 32, do not take any medication or supplement without doctor’s approval.

If you will have lab tests, will receive care from another doctor, or dentist, make sure to tell them you are having treatment with Sodium Phosphate P 32.

It is important not to get pregnant or do breastfeeding while taking Sodium Phosphate P 32. If you became pregnant or do breastfeeding, call your doctor at once.

5 Potential side effects

Sodium Phosphate P 32 may cause the following side effects: