1 What is Sotradecol?

Brand: Sotradecol

Generic: Sodium tetradecyl sulfate

Sotradecol is used to treat varicose veins. Sotradecol (Sodium tetradecyl sulfate) is a sclerosing agent. When injected into a varicose vein, it causes ‘mini’ inflammation into the area and formation of a clot that blocks the collapsed vein. Doctors use Sotradecol for resolving small varicose veins in the lower leg only. It cannot be used for large varicose veins with complications such as incompetent valves or with inflammation.

Sotradecol is an injectable drug that is injected right into the varicose vein.

You need a prescription to purchase Sotradecol. Sotradecol must be injected only by a doctor expert in blood vessel diseases, such as vascular surgeons. Serious conditions can occur if Sotradecol is misused.

2 What to Know Before Using

Your doctor will consider the following before starting treatment with Sotradecol.


If you experienced sensitivities to Sotradecol before, tell it to your doctor. You cannot use Sotradecol if you are allergic to it.

Health conditions

Make sure to tell all your health problems to the doctor before taking Sotradecol. The doctor needs to know if you have Buerger’s disease, hardening of the arteries, heart problems, blood clotting problems, or nerve injuries. Sotredecol should be used with precaution when you have these conditions.

You cannot use Sotradecol if you have the following conditions:

  • Have redness or tenderness in the vein
  • Pain, swelling or redness near the vein
  • If you are bedridden
  • Have varicose veins due to stomach or pelvic tumor that has not been removed
  • Have uncontrolled diabetes
  • Overactive thyroid
  • Tuberculosis
  • Asthma
  • Abnormal growths or tumors
  • Infection of any kind
  • Blood diseases
  • Lung disease
  • Any kind of skin disease


Tell your doctor if you are pregnant before taking Sotradecol. Sotradecol may be harmful to pregnancy. Do not take Sotradecol if you are pregnant.


Do not breastfeed if you are having Sotredecol injections.

3 Proper Usage

Sotradecol is administered by injecting it into the varicose vein. Therefore, Sotradecol should be injected by the doctor, and you can only have it in the hospital or doctor’s clinic.

You will receive Sotradecol only once, so you cannot miss a dose. Sotradecol is given by healthcare professionals, so overdosage is unlikely.

4 Precautions to Take

After receiving an injection of Sotradecol, you need to be seen by the doctor regularly. Make sure to keep up with clinic doctor appointments.

If you became pregnant or do breastfeeding shortly after receiving Sotradecol, call your doctor right away.

5 Potential Side Effects

Sotradecol may cause serious side effects. Go to your doctor if you experienced any of the following:

  • Severe allergic reaction symptoms such as rash, hives, difficulty breathing, swelling of the mouth, face, lips, or tongue.
  • Burning sensation at the injection site
  • Discoloration or redness around the vein
  • Headache
  • Wheezing
  • Itchy eyes or nose
  • Nausea
  • Pain or tenderness in the leg
  • Runny nose
  • Sneezing
  • Swelling of the leg
  • Vomiting
  • Warm sensation in the leg

Sotradecol may cause minor side effects such as:

  • Pain, itching, and lesions at the injection site
  • Sloughing of skin at the injection site

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