Stadol NS

1 What is Stadol NS?

Brand: Stadol NS

Generic: Butorphanol nasal spray

Stadol NS (Butorphanol) is a painkiller nasal spray. Doctors prescribe Stadol NS to prepare patients for surgery and relieve pain during childbirth. Stadol NS can also be given to supplement other painkillers.

Butorphanol is a narcotic that have strong painkilling properties. Stadol NS works within 15 minutes to relieve pain. Stadol NS is available in another form called simply Stadol that is given via injection. This section exclusively discusses Stadol NS.

Stadol NS requires a special prescription. Because it is a narcotic and has the potential for abuse, Stadol NS is a restricted drug.

Stadol NS can cause serious impairment of breathing and addiction, especially if not used with doctor’s supervision. 

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2 What to Know Before Using

Your doctor will consider the following before prescribing Stadol NS.


You could not use Stadol NS if you experienced allergies to Butorphanol or to other forms of Stadol before.

Risk of serotonin syndrome

Use of Stadol NS may increase the risk of serotonin syndrome, a condition that causes restlessness, agitation, rapid heart rate and high blood pressure. The risk of serotonin syndrome is increased if you are taking medicines such as those used to treat mental disorders, Parkinson’s disease, migraines, serious infections, and preventing nausea and vomiting. If you are taking these medicines, tell them to your doctor before taking Stadol NS.

Previous use and abuse of other narcotics

If you recently used narcotics or have a narcotic addiction, tell them to the doctor before taking Stadol NS. You must not use Stadol NS if you have an addiction to narcotics.

Importance of proper usae

Only take Stadol NS with doctor’s supervision. You must follow doctor’s instructions to the letter, and never take more than the prescribed amount. Taking too much Stadol NS can result in life-threatening side effects like slowed breathing. Never share Stadol NS to others. Keep Stadol NS in a secure place.

Health conditions

Tell the doctor all your health problems before taking Stadol NS. The doctor needs to know if you have any of the following health conditions:

Pregnancy and breastfeeding

Tell the doctor if you are pregnant before taking Stadol NS. Stadol NS is an FDA pregnancy category C drug, which means it can cause harm to the developing fetus when given long-term to pregnant women. Stadol NS, however, can be safely used in childbirth.

Do not breastfeed when taking Stadol NS because it may be expressed into breastmilk.

Use on children

Do not give Stadol NS to children. It is not known if Stadol NS is safe or effective in patients below 18 years old.

Use on elderly

The elderly may be more sensitive to the effects of Stadol NS. Stadol NS should be used with caution in elderly, and they must be carefully monitored and guarded against falls.

Alcohol use

Alcohol increases risks of side effects of Stadol NS. Do not take alcoholic beverages.

Drug interactions

Stadol NS can interact with several drugs and cause undesirable effects. Before taking Stadol NS, make sure to tell the doctor all the medicines you take especially the following:

  • Alcohol
  • Barbiturates
  • Tranquilizers
  • Anti-allergy medications
  • Naltrexone
  • Anti-migraine medicines such as Sumatriptan
  • Isocarboxazid
  • Iohexol
  • Iopamidol
  • Methylene
  • Metrizamide
  • Naltrexone
  • Sodium oxybate
  • Tramadol
  • Tranylcypromine

3 Proper Usage

Stadol NS is a nasal spray that you must spray inside the nose. Follow your doctor’s instructions and dosage in taking Stadol NS. Stadol NS comes with an information guide. Make sure to understand the information in this guide completely. Ask your doctor if you have questions.

Stadol NS is taken for pain. Make sure to blow your nose first before spraying Stadol NS.

The usual dose for Stadol NS is one spray (one spray is 1 mg) in one nostril. If pain relief is still not achieved within 60-90 minutes, another one spray may be given. This dosing can be repeated in 3 to 4 hours after the second dose.

You need to prime Stadol NS when using it for the first time. Remove the protective clip and pump the device 7 to 8 times until there is a fine mist. Make sure to prime the device each time you have not used Stadol NS for more than 48 hours.

After finishing administration of Stadol NS, remove the cap and rinse the device under running water.

You cannot miss a dose of Stadol NS because you only have to take it for pain.

You could overdose on Stadol NS if you sprayed too much. If this happens, call emergency medical services right away.

Keep Stadol NS at room temperature away from light and heat.

4 Precautions to Take

Only use Stadol NS as prescribed by the doctor. Do not spray more than the amount prescribed. Doing so can result in overdose.

Avoid spraying Stadol NS on the eyes. If this happens, wash the eyes with copious amounts of water for at least 5 minutes.

You must be closely monitored by the doctor when taking Stadol NS. Make sure to keep up with clinic visits and lab tests.

Stadol NS can cause unpleasant withdrawal symptoms if stopped suddenly. If you wish to discontinue using Stadol NS, call your doctor at once. The doctor will give you instructions on gradually discontinuing Stadol NS to reduce withdrawal effects.

Like other narcotics, you can become addicted to Stadol NS even if you use it in normal doses. Discuss this with your doctor.

Do not consume any amount of alcohol while taking Stadol NS.

Keep Stadol NS in a secure place away from the reach of others. Dispose empty Stadol NS bottles properly away from children and pets. 

5 Potential Side Effects

Stadol NS cause side effects, some which require medical attention. Call your doctor if you experience the following symptoms:

  • Overdose symptoms such as slow breathing, slow heartbeat, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.
  • Severe allergic reaction symptoms such as hives, difficulty breathing, skin rash, swelling of the face, mouth, throat, or lips.
  • Symptoms of dangerously high blood pressure such as a severe headache, pounding in the neck or ears, nosebleeds, confusion, anxiety, shortness of breath, irregular heartbeats, and blurred vision.
  • Symptoms of low cortisol such as nausea, vomiting, losing appetite, worsening dizziness, and weakness.
  • Impotence, loss of interest in sex
  • Infertility, or missed menses
  • Lightheadedness or fainting
  • Tremors
  • Numbness or tingling sensation anywhere in the body
  • Urinating difficulties
  • Pounding or uneven heartbeats
  • Weak or shallow breathing
  • Slow heart rate

Stadol NS may cause the following side effects that are minor: