Symlin

1 What is Symlin?

Brand: Symlin, SymlinPen

Generic: Pramlintide

Symlin injection is an amylin analogue used for the treatment of high blood sugar in patients with type 1 and types 2 diabetes, who are also using mealtime insulin and have failed to control blood sugar levels.

This drug requires a prescription.

2 What to Know Before Using

Before using Symlin, you must know all about the risks and complications associated with it.

Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children regarding the correlation of age to the effects of pramlintide injection have not been performed while safety and efficacy have not been established.

Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of pramlintide injection.

Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate. Infant risk is still undetermined when using this drug during breastfeeding.

Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Balofloxacin
  • Besifloxacin
  • Ciprofloxacin
  • Enoxacin
  • Fleroxacin
  • Flumequine
  • Gatifloxacin
  • Gemifloxacin
  • Insulin
  • Insulin Aspart
  • Recombinant Insulin
  • Bovine Insulin
  • Degludec Insulin
  • Detemir Insulin
  • Glulisine Insulin
  • Lispro
  • Lanreotide
  • Levofloxacin
  • Lomefloxacin
  • Moxifloxacin
  • Nadifloxacin
  • Norfloxacin
  • Octreotide
  • Ofloxacin
  • Pasireotide
  • Pazufloxacin
  • Pefloxacin
  • Prulifloxacin
  • Rufloxacin
  • Sparfloxacin
  • Tosufloxacin
  • Acebutolol
  • Atenolol
  • Betaxolol
  • Bisoprolol
  • Carteolol
  • Carvedilol
  • Celiprolol
  • Esmolol
  • Furazolidone
  • Iproniazid
  • Isocarboxazid
  • Labetalol
  • Levobunolol
  • Linezolid
  • Methylene Blue
  • Metipranolol
  • Metoprolol
  • Moclobemide
  • Nadolol
  • Nebivolol
  • Nialamide
  • Oxprenolol
  • Penbutolol
  • Phenelzine
  • Pindolol
  • Practolol
  • Procarbazine
  • Propranolol
  • Rasagiline
  • Safinamide
  • Selegiline
  • Sotalol
  • Timolol
  • Tranylcypromine

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects.

Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as gastroparesis, high HbA1c level, hypoglycemia, hypoglycemia, infection, or stress.

Have a question aboutHigh Blood Sugar glucose?Ask a doctor now

3 Proper Usage

To use Symlin properly, you must follow all instructions given by your doctor. Your blood sugar, blood, and urine should be tested regularly. This drug will be used at home. You will be educated on how to inject this drug at home.

This drug is injected under the skin of your stomach or upper thigh. The drug must be injected at a site that is more than 2 inches away from your insulin injection.

Insulin and pramlintide must not be injected into the same site. If there are any changes in the drug do not inject it. Throw away any used needles or syringes in their proper receptacles.

Tell your healthcare professional about any medications you are taking. The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.

The dosage of this drug you take depends on the medical problem for which you are using this drug.

The dose in adults with Type 1 diabetes is based on your blood sugar and how well your body adjusts to the drug, and this must be determined by your healthcare professional.

The starting dose is 15 micrograms injected under the skin right before each major meal. A major meal has at least 250 calories or 30 grams of carbohydrates.

Your healthcare professional may adjust your dose if necessary. Use and dose in children must be determined by your healthcare professional.

The dose in adults with Type 2 diabetes is based on your blood sugar and how well your body adjusts to the drug, and this must be determined by your healthcare professional.

The starting dose is 60 micrograms injected under the skin right before each major meal. A major meal has at least 250 calories or 30 grams of carbohydrates.

Your healthcare professional may adjust your dose if necessary. Use and dose in children must be determined by your healthcare professional.

A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the drug in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.

Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

10 Natural Ways to Lower Your Blood Sugar

4 Precautions to Take

Before using Symlin, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug.

Unwanted effects can be screened using blood tests. Alcohol intake may cause hypoglycemia. Make the necessary precautions against hypoglycemia and hyperglycemia.

Wear any identification material stating that you are a diabetic taking this drug. Check with your healthcare professional before you take any other prescription or nonprescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Symlin. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • anxiety
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool pale skin
  • cough
  • depression
  • the difficulty with swallowing
  • dizziness
  • fast heartbeat
  • headache
  • hives
  • itching or skin rash
  • increased hunger
  • nausea
  • nightmares
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • seizures
  • shakiness
  • slurred speech
  • tightness in the chest
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

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