1 What is Talwin?

Brand: Talwin

Generic: Pentazocine

Talwin injection is a narcotic analgesic used for the relief of moderate to severe pain. It may also be used before surgery or with a general anesthetic. This drug acts on the central nervous system to relieve pain.

Prolonged use of this drug can cause mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain.

Mental dependence is not likely to occur when this drug is used clinically. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly and can be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. This drug requires a prescription.

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2 What to Know Before Using

Before using Talwin, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children 1 to 16 years of age have not demonstrated any pediatric-specific problems that would limit the utility of pentazocine injection while safety and efficacy have not been established in children younger than 1 year of age.

Studies in the elderly have not reported any geriatric-specific problems that would limit the utility of pentazocine injection. Adjustments in the dose of the elderly may be required since they are more sensitive to the effects of pentazocine injection than younger adults, and are more likely to have age-related kidney problems.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Alfentanil
  • Almotriptan
  • Alphaprodine
  • Amitriptyline
  • Bromazepam
  • Buprenorphine
  • Codeine
  • Desvenlafaxine
  • Dihydrocodeine
  • Dolasetron
  • Donepezil
  • Fentanyl
  • Flibanserin
  • Fluoxetine
  • Fospropofol
  • Granisetron
  • Hydrocodone
  • Hydromorphone
  • Hydroxytryptophan
  • Levomilnacipran
  • Levorphanol
  • Lorcaserin
  • Meperidine
  • Methadone
  • Mirtazapine
  • Morphine
  • Morphine Sulfate Liposome
  • Oxycodone
  • Oxymorphone
  • Palonosetron
  • Propoxyphene
  • Safinamide
  • Selegiline
  • Sibutramine
  • Sufentanil
  • Suvorexant
  • Tapentadol
  • Tramadol
  • Trazodone
  • Vilazodone
  • Vortioxetine
  • Ziprasidone

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as:

3 Proper Usage

Proper usage of Talwin requires strict adherence to your doctor’s orders. A trained healthcare professional will be the only one to give you this drug in a hospital.

This drug may be injected into the skin, muscles, or veins. You will be switched to an oral drug that works the same way when your condition improves. Consult with your healthcare professional for any concerns.

4 Precautions to Take

Before using Talwin, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug.

Increased doses of this drug can develop dependence while prolonged uses can cause severe constipation. You may be advised to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet to prevent constipation.

Inform your healthcare professional immediately if you notice any symptoms at the injection site such as:

  • Depressed or indented skin
  • Blue-green to black skin discoloration
  • Pain, redness, or peeling of the skin

This drug will potentiate the effects of alcohol and other CNS such as:

  • Antihistamines or drug for allergies or colds
  • Sedatives
  • Tranquilizers
  • or Sleeping drug other prescription pain drug or narcotics
  • Drug for seizures or barbiturates
  • Muscle relaxants, or anesthetics
  • Including some dental anesthetics

Check with your healthcare professional before you take any of the drugs listed above while you are using this drug. This drug may make you dizzy, drowsy, confused, or disoriented. Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous.

Seek immediate medical attention if you have symptoms of anaphylaxis such as:

  • Rash
  • Itching
  • Hoarseness
  • Trouble breathing
  • Trouble swallowing
  • Any swelling of your hands, face, or mouth while you are using this drug

Check with your healthcare professional before you stop using the drug if you have been using this drug regularly for several weeks or longer. Your healthcare professional may want slowly taper the amount you are using before stopping it completely to help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as:

  • Abdominal or stomach cramps
  • Anxiety
  • Fever
  • Nausea
  • Runny nose
  • Sweating
  • Tremors
  • Trouble with sleeping

Consult with your healthcare professional before taking any other prescription or nonprescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Talwin. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Black, tarry stools
  • Blistering
  • Peeling, or loosening of the skin
  • Chest pain
  • Chills
  • Cough
  • Diarrhea
  • Fast, pounding, or irregular heartbeat or pulse
  • Fever
  • Itching
  • Joint or muscle pain
  • Painful or difficult urination
  • Red, irritated eyes
  • Red skin lesions
  • Often with a purple center
  • Shakiness in the legs, arms, hands, or feet
  • Shortness of breath
  • Sore throat
  • Sores, ulcers, or white spots on the lips or in the mouth
  • Swelling or puffiness of the face
  • Swollen glands
  • Trembling or shaking of the hands or feet
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Blistering
  • Crusting
  • Irritation
  • Itching, or reddening of the skin
  • Blue-green to black skin discoloration
  • Bluish lips or skin
  • Blurred vision
  • Burning
  • Crawling
  • Itching
  • Numbness
  • Prickling
  • "Pins and needles", or tingling feelings
  • Cold
  • Clammy skin
  • Confusion
  • Cough
  • Cracked
  • Dry, or scaly skin
  • Decrease in frequency of urination
  • Decrease in urine volume
  • Depression
  • Difficult or troubled breathing
  • Difficulty in passing urine
  • Dizziness
  • Fainting
  • Fast or slow heartbeat
  • Fast, weak pulse
  • Flushed skin
  • Hardening or thickening of the skin
  • Headache
  • Increased sweating
  • Irregular, fast, slow, or shallow breathing
  • Lightheadedness
  • Nervousness
  • Pain, redness, or sloughing of the skin at the injection site
  • Pale or blue lips, fingernails, or skin
  • Pounding in the ears
  • Rapid breathing
  • Small lumps under the skin at the injection site
  • Stinging at the injection site
  • Sweating
  • Swelling of the lower legs or arms
  • Tightness in the chest
  • Very slow breathing
  • Weight gain
  • Wheezing

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.