Talwin NX

Talwin NX is used for the relief moderate to severe pain. This drug collectively acts on the central nervous system to relieve pain and on the CNS to block the effects of narcotics, especially the "high'' feeling that makes you want to use them.

It will not produce any narcotic-like effects or cause mental or physical dependence. Prolonged use of this drug can cause mental or physical dependence.

However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence will not happen when this drug is used for clinical purposes.

Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly but it can be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. This drug requires a prescription.

Before using Talwin NX, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children younger than 12 years of age regarding the correlation of age to the effects of pentazocine and naloxone combination have not been performed while safety and efficacy have not been established.

Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the usefulness of pentazocine and naloxone combination. Adjustments in the dose of the elderly may be required since they are more likely to have age-related liver, kidney, or heart problems.

Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

• Alfentanil
• Almotriptan
• Alphaprodine
• Amitriptyline
• Bromazepam
• Buprenorphine
• Codeine
• Desvenlafaxine
• Dihydrocodeine
• Dolasetron
• Donepezil
• Fentanyl
• Flibanserin
• Fluoxetine
• Fospropofol
• Granisetron
• Hydrocodone
• Hydromorphone
• Hydroxytryptophan
• Levomilnacipran
• Levorphanol
• Lorcaserin
• Meperidine
• Methadone
• Mirtazapine
• Morphine
• Morphine Sulfate Liposome
• Naloxegol
• Oxycodone
• Oxymorphone,
• Palonosetron
• Propoxyphene
• Safinamide
• Selegiline
• Sibutramine
• Sufentanil
• Suvorexant
• Tapentadol
• Tramadol
• Trazodone
• Vilazodone
• Vortioxetine
• Ziprasidone
• Clonidine
• or Yohimbine

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as:

• Addison's disease
• Alcohol abuse
• Asthma
• Brain tumor
• Breathing problems
• Cholecystitis
• Chronic obstructive pulmonary disease
• Cor pulmonale
• Drug dependence
• Enlarged prostate
• Gallbladder disease or gallstones
• Head injuries
• Hypothyroidism
• Intestinal or bowel blockage
• Kyphoscoliosis
• Mental illness
• Pancreatitis
• Problems with passing urine
• Respiratory depression
• Stomach or digestive problems
• Heart attack
• Cardiovascular disease
• Hypertension
• Porphyria
• Seizures
• Kidney or liver disease

Proper usage of Talwin NX requires strict adherence to your doctor’s orders. Taking increased doses for a prolonged time can cause mental or physical dependence.

Inform your healthcare professional if you smoke tobacco, as this can change how well this drug works. The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.

The dosage of this drug you take depends on the medical problem for which you are using this drug. Adults, teenagers, and children 12 years of age and older with moderate to severe pain are initially given one tablet every 3 or 4 hours if necessary. Your healthcare professional may adjust your dose as needed.

The dose must not exceed 12 tablets per day. Use and dose in children younger than 12 years of age must be determined by your healthcare professional. A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the drug in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

Before using Talwin NX, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug.

This drug will potentiate the effects of alcohol and other CNS depressants such as:

• Antihistamines or drug for allergies or colds
• Sedatives
• Tranquilizers or sleeping drug
• Other prescription pain drug or narcotics
• Drug for seizures or barbiturates
• Muscle relaxants
• Anesthetics, including some dental anesthetics

Check with your healthcare professional before you take any of the drugs listed above while you are using this drug. You must only take the prescribed dose since this drug cab be –habit forming. This drug can cause:

• Dizziness
• Drowsiness
• Lightheadedness

Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous. Prolonged use of this drug can cause severe constipation. You may be advised to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet to prevent constipation.

Check with your healthcare professional before you stop using drug if you have been using this drug regularly for several weeks or longer.

Your healthcare professional may want slowly taper the amount you are using before stopping it completely to help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as:

• Abdominal or stomach cramps
• Anxiety
• Fever
• Nausea
• Runny nose
• Sweating
• Tremors
• Trouble with sleeping

This drug has teratogenic potential which can harm your baby while taking this drug. Inform your healthcare professional immediately if you think you are pregnant or if you plan to become pregnant while using this drug. Consult with your healthcare professional before taking any other prescription or nonprescription drugs, and herbal or vitamin supplements.

As with many medications, there are several potential side effects associated with Talwin NX. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

• Black, tarry stools
• Blistering
• Peeling, or loosening of the skin
• Chest pain
• Chills
• Cough
• Diarrhea
• Fast, pounding, or irregular heartbeat or pulse
• Fever
• Itching
• Joint or muscle pain
• Painful or difficult urination
• Red, irritated eyes
• Red skin lesions
• Often with a purple center
• Shakiness in the legs, arms, hands, or feet
• Shortness of breath
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Swelling or puffiness of the face
• Swollen glands
• Trembling or shaking of the hands or feet
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Blistering
• Crusting
• Irritation
• Itching, or reddening of the skin
• Blue-green to black skin discoloration
• Bluish lips or skin
• Blurred vision
• Burning
• Crawling
• Itching
• Numbness
• Prickling
• "Pins and Needles" or tingling feelings
• Cold
• Clammy skin
• Confusion
• Cough
• Cracked, dry or scaly skin
• Decrease in frequency of urination
• Decrease in urine volume
• Depression
• Difficult or troubled breathing
• Difficulty in passing urine
• Dizziness
• Fainting
• Fast or slow heartbeat
• Fast, weak pulse
• Flushed skin
• Hardening or thickening of the skin
• Headache
• Increased sweating
• Irregular, fast, slow, or shallow breathing
• Lightheadedness
• Nervousness
• Pain, redness, or sloughing of the skin at the injection site
• Pale or blue lips
• Fingernails, or skin
• Pounding in the ears
• Rapid breathing
• Small lumps under the skin at the injection site
• Stinging at the injection site
• Sweating
• Swelling of the lower legs or arms
• Tightness in the chest
• Very slow breathing
• Weight gain
• Wheezing

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.