1 What is Thalitone?

Brand: Thalitone

Generic: Chlorthalidone

Thalitone is a diuretic used alone or together with other drugs to treat hypertension.

In hypertension there is increased the workload of the heart and arteries which can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, heart attacks, or kidney failure.

These health problems can be prevented when blood pressure is controlled. Thalitone is also used to treat:

  • Edema secondary to congestive heart failure
  • Severe liver disease (cirrhosis)
  • Kidney disease
  • Treatment with a hormone or steroid medicine

This drug increases urine output thereby reducing the amount of water in the body which helps reduce fluid retention. Thalitone is a prescription drug.

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2 What to Know Before Using

Before using Thalitone, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies on the relationship of age to the effects of chlorthalidone in the pediatric population have not been performed while safety and efficacy have not been established. No studies suggest a relationship of age to the effects of chlorthalidone in geriatric patients.

Elderly patients may require an adjustment to their dosage due to increased likelihood of having age-related liver, kidney, or heart problems. No evidence of harm to the fetus of animals has been found out in studies.

There are no adequate studies in pregnant women or animal studies. Studies failed to demonstrate a risk to the fetus of pregnant women.

There are no studies suggesting an infant risk when taking this drug during breastfeeding. Consult your healthcare provider about the benefits and risks of this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Acetyldigoxin
  • Arsenic
  • Trioxide
  • Bepridil
  • Deslanoside
  • Digitalis
  • Digitoxin
  • Digoxin
  • Dofetilide
  • Droperidol
  • Flecainide
  • Ketanserin
  • Levomethadyl
  • Lithium,
  • Metildigoxin
  • Sotalol
  • Aceclofenac
  • Acemetacin
  • Alacepril
  • Amtolmetin
  • Guacil
  • Aspirin
  • Benazepril
  • Bromfenac
  • Bufexamac
  • Captopril
  • Celecoxib
  • Choline Salicylate
  • Cilazapril
  • Clonixin
  • Delapril
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dipyrone
  • Droxicam
  • Enalapril
  • Enalaprilat
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbina
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Fosinopril
  • Gossypol
  • Ibuprofen
  • Lysine
  • Imidapril
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Licorice
  • Lisinopril
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib,
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Moexipril
  • Morniflumate
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Pentopril
  • Perindopril
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Proglumetacin
  • Propionic Acid
  • Propyphenazone
  • Proquazone
  • Quinapril
  • Ramipril
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • Spirapril
  • Sulindac
  • Temocapril
  • Tenoxicam
  • Tiaprofenic Acid
  • Tolfenamic Acid
  • Tolmetin
  • Trandolapril
  • Valdecoxib
  • Warfarin
  • Zofenopril

Intake of specific food or using alcohol or tobacco with chlorthalidone is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems especially:

Kidney Liver disease may potentiate the effect of this drug because of slower excretion from the body.

3 Proper Usage

To use Thalitone properly, you must follow all instructions given by your doctor. The treatment of hypertension may include weight control and changes in the types of foods you eat, especially foods high in sodium or potassium.

Consult with your healthcare professional before changing your diet. Hypertensive patients usually feel normal and will only feel the symptoms when extensive damage already occurred.

Compliance with your drugs and regular checkups are important to control your hypertension.

You may have to do this for the rest of your life, since when left uncontrolled it can cause serious problems, such as:

The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.

The dosage of this drug you take depends on the medical problem for which you are using this drug.

  • Adults with edema are usually prescribed with oral dosage forms (capsules) of 50 to 100 milligrams once a day.
  • For children with edema, the dose must be determined by your healthcare professional based on their body weight.
  • Adults with hypertension are usually prescribed with oral dosage forms (capsules) of 25 milligrams once a day.

A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

4 Precautions to Take

Before using Thalitone, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood tests.

Consult with your healthcare professional if you have any symptoms of hypokalemia such as:

  • Convulsions or seizures
  • Decreased urine
  • Drowsiness
  • Dry mouth
  • Excessive thirst
  • Muscle pains or cramps
  • Nausea or vomiting
  • Increased heart rate or pulse
  • Unusual tiredness or weakness

This drug may cause some people to become lightheaded. If this happens, do not anything dangerous such as driving, use machines, or do anything else with a potential hazard.

Alcohol intake may also worsen dizziness. Consult with your healthcare professional before taking prescription or non-prescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Thalitone.

Symptoms of unknown incidence can either be one of the following:

  • abdominal or stomach pain
  • back, leg or stomach pains
  • black, tarry stools
  • bleeding gums
  • blisters on the skin
  • blood in urine or stools
  • bloody or cloudy urine
  • blue lips and fingernails
  • blurred vision
  • burning
  • crawling
  • itching
  • numbness
  • prickling
  • "pins and needles" or tingling feelings
  • chest pain
  • chills
  • clay-colored stools
  • cold sweats
  • confusion
  • constipation
  • a cough or hoarseness
  • coughing that sometimes produces a pink frothy sputum
  • coughing up blood
  • darkened urine
  • the decrease in urine output or decrease in urine-concentrating ability
  • decreased frequency or amount of urine
  • diarrhea
  • difficult, fast or noisy breathing, sometimes with wheezing difficulty swallowing
  • dizziness, faintness or lightheadedness when getting up from a lying or sitting position suddenly
  • dry mouth
  • fast heartbeat
  • the feeling of constant movement of self or surroundings
  • fever
  • flushed, dry skin fruit-like
  • breath odor
  • the general feeling of discomfort or illness
  • the general feeling of tiredness or weakness
  • headache
  • hives
  • increased blood pressure
  • increased hunger
  • increased sensitivity of skin to sunlight
  • increased sweating
  • increased thirst
  • increased urination
  • indigestion
  • itching
  • joint pain
  • stiffness or swelling
  • loss of appetite
  • lower back or side pain
  • muscle cramps or pain
  • nausea
  • nosebleeds
  • numbness
  • tingling, pain or weakness in hands or feet
  • pain in joints or muscles
  • painful or difficult urination
  • pains in stomach, side or abdomen, possibly radiating to the back
  • pale skin
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • redness or other discoloration of the skin
  • redness, soreness or itching skin
  • seizures
  • the sensation of spinning
  • severe sunburn
  • shortness of breath
  • skin rash
  • sores, ulcers or white spots on lips or in the mouth
  • sores, welting or blisters
  • sugar in the urine
  • sweating, swelling in legs and ankles
  • swelling of the face, fingers or lower legs
  • swollen or painful glands
  • tenderness of salivary glands
  • thickening of bronchial secretions
  • tightness in the chest
  • trembling
  • troubled breathing
  • unexplained weight loss
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight loss
  • vomiting of blood weight gain
  • yellow eyes or skin

Immediately inform your healthcare professional if you experience these side effects. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.

Inability to have or keep an erection increase or loss in sexual ability, desire, drive, or performance, increased or decreased interest in sexual intercourse, menstrual changes, skin and blisters have been reported but have unknown incidence. Report any side effects to the FDA hotline at 1-800-FDA-1088.