1 What is Thorazine?

Brand: Thorazine

Generic: Chlorpromazine

Thorazine is a drug used in the treatment of psychotic disorders such as schizophrenia and in the control of nausea and vomiting. This drug is also used to relieve restlessness and apprehension before surgery as well as intractable hiccups, and to treat intermittent porphyria and tetanus (as an adjunct).

Chlorpromazine is available as a film-coated tablet in 10 mg, 25 mg, 50 mg, 100 mg and 200 mg preparations. This drug is also available in the injectable form.

You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.

Thorazine may interact with medications such as:

  • Alpha blockers such as:
    • Prazosin
  • Anticholinergic/antispasmodic drugs such as:
    • Atropine
    • Dicyclomine
    • Scopolamine
  • Drugs that increase the amount of dopamine in your body such as:
    • Cabergoline
    • Levodopa
    • Pergolide
    • Ropinirole
  • Guanethidine
  • Warfarin
  • Pindolol
  • Propranolol
  • Drugs to treat seizures such as:
    • Carbamazepine
    • Phenobarbital
    • Phenytoin
  • Amiodarone
  • Dofetilide
  • Pimozide
  • Procainamide
  • Quinidine
  • Sotalol
  • Macrolide antibiotics such as:
    • Erythromycin
  • Alcohol
  • Antihistamines such as:
  • Drugs for sleep or anxiety such as:
    • Alprazolam
    • Diazepam
    • Zolpidem
  • Muscle relaxants
  • Narcotic pain relievers such as:
    • Codeine
  • Bupropion
  • Isoniazid (INH)
  • Theophylline
  • Tramadol
  • Tricyclic antidepressants such as:

Side Effects: There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling

Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to chlorpromazine or to other phenothiazine drugs such as:
    • Perphenazine
    • Thioridazine
  • Liver problems
  • Kidney problems
  • Heart problems such as:
    • Mitral Valve Insufficiency
    • Abnormal Heart Rhythm
  • Low blood pressure
  • Blockage of the intestines
  • Glaucoma
  • Seizures
  • Enlarged prostate
  • Breathing problems such as:
  • Blood disorders such as:
    • Bone Marrow Depression
    • Low Red/White/Platelet Blood Cell counts
  • Low levels of calcium in the blood
  • Loss of too much body water (dehydration)
  • Breast cancer
  • Brain disorder/tumor/injury
  • Exposure to organophosphate insecticides
  • Pheochromocytoma
  • Drug/alcohol/substance abuse
  • Parkinson's disease
  • Certain heart problems
  • Family history of certain heart problems
    • QT prolongation in the EKG
    • Sudden cardiac death

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