Generic: Olmesartan, Amlodipine, and Hydrochlorothiazide
Tribenzor can be used alone or with other drugs for the treatment of hypertension.
Hypertension adds to the workload of the heart and arteries which can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.
The risk of strokes and heart attacks can be reduced when blood pressure is lowered.
This drug combination collectively works by blocking a substance in the body that causes vasoconstriction resulting to relaxation of the blood vessels and lower blood pressure and increases urine output.
A lower blood pressure will increase the supply of blood and oxygen to the heart. This drug requires a prescription.
2 What to Know Before Using
Before using Tribenzor, you must know all about the risks and complications associated with it.
Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.
Studies in children regarding the correlation of age to the effects of olmesartan, amlodipine, and hydrochlorothiazide combination have not been performed while safety and efficacy have not been established.
Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of olmesartan, amlodipine, and hydrochlorothiazide combination.
Risks to the fetus have been reported in studies of pregnant women but these may be outweighed by the benefits of therapy in a life threatening situation or a serious disease.
Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as:
Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors
other Antihypertensive drugs
Cholestyramine and Colestipol resins
Nondepolarizing skeletal muscle relaxants
Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects.
Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.
Inform your healthcare professional if you have any other medical problems such as:
To use Tribenzor properly, you must follow all instructions given by your doctor. The treatment of hypertension may include weight control and changes in the types of foods you eat, especially foods high in sodium.
Consult with your healthcare professional before changing your diet. Hypertensive patients usually feel normal and will only feel the symptoms when extensive damage already occurred. Compliance with your drugs and regular checkups are important to control your hypertension.
You may have to do this for the rest of your life, since it can cause serious problems, such as heart failure, blood vessel disease, stroke, or kidney disease when left uncontrolled.
The dose of this drug will be variable for different patients. You can take this drug with or without food. If you are also using colesevelam (WelcholВ®), take it at least 4 hours after taking TribenzorВ®.
The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.
The dosage of this drug you take depends on the medical problem for which you are using this drug. Adults with high blood pressure are given one tablet once a day.
Your doctor may adjust the dose as needed. The dose must not exceed 40 milligrams of olmesartan, 10 mg of amlodipine, and 25 mg of hydrochlorothiazide per day.
Use and dose in children must be determined by your healthcare professional. A missed dose should be taken as soon as possible.
However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.
Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
Before using Tribenzor, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug.
Unwanted effects can be screened using blood and urine tests. This drug has teratogenic potential and it is recommended to use an effective form of birth control to keep from getting pregnant.
Inform your healthcare professional immediately if you think you have become pregnant while using this drug. This drug may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position.
Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning.
Check with your healthcare professional immediately if you become sick while taking this drug, especially if you have severe nausea, vomiting, or diarrhea that does not stop, as these conditions may cause you to lose too much water and lead to low blood pressure.
It is recommended to increase water intake during exercise or in hot weather to replenish the water lost by sweating. This drug may cause angina or a heart attack in certain patients with severe heart or blood vessel disease.
Check with your healthcare professional immediately if you are having chest pain or discomfort, fast or irregular heartbeat, nausea or vomiting, pain or discomfort in the arms, jaw, back, or neck, shortness of breath, or sweating.
Check with your healthcare professional immediately if you have signs of a serious eye problem such as blurred vision, difficulty with reading, eye pain, or any other change in vision occurs during or after treatment.
You may be referred to an ophthalmologist to have your eyes checked. This drug may affect blood sugar levels. Diabetic patients may notice a change in the results of blood or urine glucose tests.
Inform your healthcare professional immediately if you have severe, chronic diarrhea with weight loss that developed months to years after taking this drug.
Consult with your healthcare professional before taking any other prescription or nonprescription drugs for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.
5 Potential Side Effects
Make sure you meet with your doctor in using Tribenzor to avoid unwanted potential side effects.
Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:
bloating or swelling of the face, arms, hands, lower legs or feet
Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.
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