1 What is Vazculep?

Brand: Vazculep

Generic: Phenylephrine

Vazculep injection is a selective α1-adrenergic receptor agonist used for the treatment of hypotension that may occur during surgery.

This drug is to be given only by or under the direct supervision of your healthcare professional.

2 What to Know Before Using

Before using Vazculep, you must know all about the risks and complications associated with it. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children regarding the correlation of age to the effects of phenylephrine injection have not been performed while safety and efficacy have not been established. Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of phenylephrine injection.

Adjustments in the dose of the elderly may be required since they are more likely to have kidney, liver, or heart problems. Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate. Infant risk is still undetermined when using this drug during breastfeeding.

Discuss with your healthcare professional about the potential risks and benefits of taking this drug while breastfeeding. Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Linezolid
  • Rasagiline
  • Selegiline
  • Amitriptyline
  • Amoxapine
  • Clomipramine
  • Desipramine
  • Dothiepin
  • Doxepin Imipramine
  • Iobenguane
  • I 123
  • Lofepramine
  • Nortriptyline
  • Opipramol
  • Protriptyline
  • Trimipramine

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as:

3 Proper Usage

Proper usage of Vazculep requires strict adherence to your doctor’s orders. A trained healthcare professional will be the only one to give you this drug in a hospital. This is administered intravenously through a needle placed in one of your veins.

4 Precautions to Take

Before using Vazculep, there are some precautions you must take. Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood tests. This drug may cause a permanent depression under the skin at the injection site.

Inform your healthcare professional immediately if you notice any side effects at the injection site such as depressed or indented skin, blue-green to black skin discoloration, or pain, redness, or sloughing of the skin. Consult with your healthcare professional before taking any other prescription or nonprescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

Make sure you meet with your doctor in using Vazculep to avoid unwanted potential side effects. Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Blurred vision
  • Chest pain or discomfort
  • Difficult or Labored breathing
  • Dizziness
  • Fainting
  • Fast, Slow, or Irregular heartbeat
  • Headache
  • Nausea or Vomiting
  • Nervousness
  • Pain in the shoulders, arms, jaw, or neck
  • Pounding in the ears
  • Sweating
  • Tightness in the chest
  • Unusual tiredness
  • Symptoms of overdose such as feeling of fullness in the head, pounding or rapid pulse
  • Tingling in the arms or legs
  • Vomiting

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials