1 What is Vexol?

Brand: Vexol

Generic: Rimexolone

Vexol is a prescription-only steroid eye suspension used to suppress swelling (inflammation) of the eye associated with eye surgery or certain eye conditions. 

2 What to Know Before Using

Before using Vexol, you must know all about the risks and complications associated with it. Together with your doctor, you can decide whether the medication will do you more goods than the harms. 

Here are some factors to be considered before deciding to use this medicine:

Allergies: Inform your doctor about the allergies you have, such as to this medication, other medications, or to foods, dyes, or preservatives.

Pediatric: Safety and efficacy have not been well documented.

Geriatric: Safety and efficacy have not been well documented.

Drug Interactions: Though usually not recommended, your doctor may decide, after adjusting dose or frequency of one or both medicines, to use this medicine with any of the following medicines:

  • Bupropion
  • Pixantrone

Other Interactions: Taking your medicine together with certain foods or items such as alcohol or tobacco may cause undesirable interactions. Talk to your doctor to know if using this medicine with food, alcohol, or tobacco is safe.

Inform your doctor if you have any other medical conditions, including:

  • Eye diseases that cause corneal thinning: Using rimexolone in the eyes may result in perforation of the cornea.
  • Infection of the eye caused by a fungus, virus including herpes, and yeast
  • Other eye infection

If you already have an eye infection, using ophthalmic rimexolone can cause further worsening of the infection. Sometimes, a new infection may also start.

3 Proper Usage

To use Vexol properly, you must follow all instructions given by your doctor. Properly shake the container before each use.

How to Use:

  • Wash your hands properly using soap and water.
  • Lift your chip up and, create a gap in the region of the eye near the lower eyelid by gently pulling the lower eyelid away from your eyes.
  • Instill the recommended drops of the medicine into this gap.
  • Shut your eyes.
  • Blinking during this time is not recommended.
  • Do not open your eyes and gently press the inner corner of the eye with your finger for 1 or 2 minutes to facilitate absorption of the medicine.
  • In case you feel enough dose has not been instilled, take another drop.
  • To reduce contamination by the germs, avoid contact between the applicator tip and any surface (eyes included).
  • Close the container properly after each use.

Dosing: For best results, follow your doctor to know what amount of medicine you should take in a single dose. The doses of a medicine can differ according to the conditions for which it is being prescribed, your age and your overall health status. Remember your doses can differ. Consult your doctor if you have anything to ask. The dose of eye drops for:

Inflammation after surgery:

  • Adults: 24 hours after surgery, instill 1 or 2 drops in the diseased eye every six hours and continue for the next 14 days.
  • Children: Your doctor will decide the use and dose.

Anterior uveitis (inflamed iris of the eye):

  • Adults
    • Week I: Instill 1 or 2 drops in the diseased eye at an interval of one hour throughout the waking hours.
    • Week II: Instill 1 drop in the diseased eye at an interval of 2 hours throughout the waking hours. Follow your doctor’s instructions for decreasing the frequency of application.
  • Children: Your doctor will decide the use and dose.

Missed Dose: Take your missed dose once you remember but avoid it if it’s time to take your next dose, and follow your normal dosing schedule. Avoid taking double doses to make up for the missed dose.


  • Store in a closed container at room temperature.
  • Keep away from heat, moisture, and direct light.
  • Do not freeze.
  • Keep away from children.
  • Discard any unused or expired medicines.

4 Precautions to Take

In using Vexol, you must be careful and take some precautions as advised by your doctor, your eyes should be regularly checked by an ophthalmologist (eye specialist).

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Vexol.

Consult your doctor immediately if you have any of the following side effects:

Less common or rare:

  • Dry or watery eye
  • Nasal congestion or drainage
  • Red, irritated or painful eye
  • Sore throat
  • Swollen eyelid lining
  • Uneasy feelings in the eye
  • Unusual eye discharge
  • Vision problems including a blurry vision

Talk to your doctor if any other side effects persist or worry you. The side effects of the medicine are not limited to the ones listed above.

Call your doctor immediately if you experience any side effects that are uncommon or worry you. To report side effects to the FDA, contact at 1-800-FDA-1088.