1 What is Zylet?

Brand: Zylet

Generic: Loteprednol and Tobramycin

Zylet is an ophthalmic (eye) solution used to treat bacterial infection of an eye. It is a combination of a corticosteroid (Loteprednol) and antibiotic (Tobramycin).

It reduces inflammation and swelling and protects the eye from certain bacterial infections. It is available in a suspension form only with your doctor’s prescription.

2 What to Know Before Using

Before using Zylet, you must know all about the risks and complications associated with it.

Before starting the treatment your doctor should be informed about condition such as:

Allergy: Inform your doctor if you are allergic to any food, preservatives, dyes, or had an allergic reaction when you used this drug before.

Children: There are no adequate studies which prove its safety in children.

Elderly: This medicine does not cause any different side effects or problem than it does in younger adults.

Pregnancy: It is a category C drug. It is not safe in pregnancy. It may cause harmful effects to an unborn baby.

Breast Feeding: There are no adequate studies which prove that Loteprednol and Tobramycin pass into breast milk. If you are using Loteprednol and Tobramycin while nursing, discuss it with your doctor for possible risk factors.

Drug Interactions: It may interact with other drugs. Your doctor should be informed of any other medicines which you are taking. He may want to change the dosage or drug.

Some of them are listed below:

  • Certain diuretic medicines (furosemide)
  • Cyclosporine
  • Nonsteroidal anti-inflammatory medicines (NSAIDS) (ibuprofen)
  • Other medicines containing aminoglycoside antibiotics (tobramycin, gentamicin) because the risk of their side effects may be increased by Loteprednol/Tobramycin drops.

Several other conditions may reduce its effectiveness.

Make sure you inform your doctor of conditions such as:

  • If you have glaucoma
  • Thinning of certain parts of the eye (the cornea or the sclera).
  • History of herpes simplex infection.
  • Cataract surgery
  • Smallpox eye infection
  • Tuberculosis eye infection
  • Varicella (chickenpox) eye infection
  • Viral (caused by a virus) eye infection: Should not be used in patients with these conditions.

3 Proper Usage

Proper usage of Zylet requires strict adherence to your doctor’s orders. Ask your pharmacist if you have any queries. Shake well before each use.

To use Loteprednol/Tobramycin drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch.

Drop the medicine into the pouch and gently close your eyes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

Dosage: It is different for different patients. Dosage mentioned below is an average dose.it is best to take each dose at equally spaced times a day and night. You must follow your doctor’s instructions.

Adults: Use one or two drops in the affected eye every 4 to 6 hours.

Missed dose: If you miss a dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and continue your daily schedule. Do not double the dose.

Storage: Store it at room temperature. Keep it away from children.

4 Precautions to Take

Before using Zylet, there are some precautions you must take. Your doctor should check your daily progress at regular visits.

If it is not improving your symptoms, or your symptoms become worse, inform your doctor right away.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Zylet. Some people may experience none or minor side effects.

Consult with your doctor if they become problematic or frequent:

Most common are:

  • Blurred vision
  • Change in vision
  • Feeling like something is in the eye
  • Increased intraocular pressure
  • Loss of vision
  • Pain or irritation of the clear front part of the eye
  • Sensitivity of the eyes to light

Less common are:

  • Blurred vision or seeing blue-green halos around objects
  • Decreased vision
  • Difficulty seeing at night
  • Discharge from the eye
  • Dry eyes
  • Eyelid burning, redness, itching, pain, or tenderness
  • Fast heartbeat
  • Fever
  • Hives
  • Hoarseness
  • Lid itching and swelling
  • Pain in the eye
  • Shortness of breath
  • Stiffness or swelling
  • Swelling of the eyelids, face, lips, hands, or feet
  • Tightness in the chest
  • Troubled breathing or swallowing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.