“Acne medicine?”

We typically recommend avoiding Differin gel and other retinoids (retinoic acid) medications in pregnancy, because of the potential risk to the developing fetus.

Depends on your opinion. The manufacturer says no (they are protecting their butts). The (limited) research has not found any fetal effects that are likely to be caused by the retinoid medication in Differin. The amount of difference absorbed through the skin is very small, which makes it even less likely to cause a problem. So, from my point of view, you can keep using the gel, with very little risk of a problem. This, of course, doesn't mean that you won't have something wrong with the baby (3-5% risk in every pregnancy); it just is very unlikely to be due to the Differin. If you want to be safer, don't use it until after 13-14 weeks, by which time, all the parts of the baby are formed, so a physical birth defect can't happen after that. Or you can not worry about it, because we love you for your mind, not your skin. Good luck.