“Amputation ”

No, leg transplant is not something that is done.

Yes, the transplantation exists, but rare.

Your intention is more than laudable, it is heroic and shows amazing friendship! No, that has never been done before. And it will never be done, because transplants are done with the intent of saving the life or function of the patient when there is no other alternative. Because there are many alternatives for patients to still ambulate even if they are amputees, this will never be taken into consideration. The risks greatly outweigh the benefits. When you donate a kidney that is one thing but when you donate something that the recipient could live without , the risk of rejection of the transplant makes the procedure unthinkable. What your friend needs to understand is that, many times, her quality of life will be much better after an amputation than before. Many times an amputation is postponed because of the patient fear of what they will become, not understanding that, by going two-three times to the wound clinic every week and then, after years of doing that up, an amputee nonetheless, makes the patient slave of his or her wounded leg. Best regards, R. Constantine

Wow! First of all, you are more than anyone can ever dream of in terms of a friend. I am not a vascular surgeon but I don't believe this would be possible. As with any transplant, if you're not an HLA match her/his body would reject it. Additionally, I don't believe a surgeon would amputate you to give them a leg. That would be ethical issues as it goes against our hippocratic oath of "first do no harm." But I commend you for your selflessness and kind heart.