“Medications together?”

There are no direct or dangerous drug interactions with acetaminophen while on mirtazapine. Please note the dosage instructions for Tylenol carefully. Do not exceed 3,000–4,000 mg per day of acetaminophen, as excessive amounts can cause liver damage. As for the toothache, Tylenol may help manage the pain, but it won’t treat the underlying cause of the toothache, which could be an infection or dental issue. It’s important to see a dentist or healthcare provider as soon as possible, especially since the pain has been ongoing. If the pain is severe or accompanied by fever, swelling, or difficulty swallowing, seek urgent care.

There are no significant interaction between the two medications, however, you need to make sure that you do not take Tylenol for more than three consecutive days, if pain lasts for longer. Tylenol needs to be spaced every 4-6 hrs. overdose on it might cause liver toxicity.