Give little time more listen to what your Surgeon is advising you. At this stage you need to drain the seroma in the care of your Surgeon's team.
There is no evidence that Botox will help.
You either have a seroma or a sialocele. The former is an accumulation of lymphatic and wound fluid in a cavity after surgery where a space was created between the skin and the underlying tissue. A sialocele is an accumulation of saliva type fluid originating from the Parotid gland which is essentially a saliva secreting gland. In both instances, one expects this to be self limiting and to resolve in time.
For a seroma, a suction drain will suffice if left in for 1 - 2 weeks. Alternatively, one can have needle aspirations every so often until it settles spontaneously. As far as a sialocele goes, the gland will produce more saliva when eating sour or acid type foods such as citrus, apples, vinegar etc. One has to stay away from such foods for a while and still have needle aspirations too every 2 weeks or so. It should settle over time.
One can differentiate between a seroma and a sialocele by doing a fluid amylase assessment. This is a salivary enzyme which will not be present in a true seroma, but in a sialocele. Botox injection into the gland or revision surgery have been tried in the past to manage a sialocele, but surgery carries further risks for nerve injury and should not be chosen as a firstline step. It should really clear up with sequential aspirations over a period of 3 months. It is possible that a salivary fistula may develop and again this will be managed the same way. It is uncommon to have to undergo further surgery for this.
Joseph E. Ronaghan, MD, FACS, FICS