Pathologist Questions Pathologist

What can lead to pediatric liver disease?

My wife and I are about to have a child. We know that liver disease runs in the family. What can lead to pediatric liver disease?

1 Answer

Causes of pediatric diseases are Inherited Hemochromatosis (increased iron in the body), Alpha-1-antitrypsin deficiency or cystic fibrosis, (inherited disease that also affect the lungs), heart problems that reduce the blood supply to the liver or lead to back-up flow in the liver. The most common pediatric liver disease is Nonalcoholic Fetty Liver Disease (NAFLD). Is the most common form of chronic liver disease in children and adolescents. Studies reveal that 5% to 10% of children have NAFLD. The most common causes are hepatitis and other viruses, and alcohol. In very young children. In very young children, cirrhosis is the most often caused by genetic (inherited) liver problem such as biliary atresia. Early symptoms are feeling unwell, tired, loss of appetite, feeling sick, tenderness or pain around the liver, spider angiomas (spider-like small blood capillaries on the skin above the waist), blotchy red palms and disturbed sleep pattern. Liver damage can often be reversed with a well-managed treatment plan. Consult your pediatric. Thank you.