Gastroenterologist Questions Colonic Polyps

What percentage of biopsied polyps are cancerous?

I just had a colonoscopy, and the doctor performed a biopsy on a polyp he found. Now I'm waiting for the results. What percentage of colon polyps are cancerous?

3 Answers

Very low percentage, less than 1%. The chance that a polyp has cancer in it increases with larger polyp size. Cancer will almost never be found in a polyp < 1 cm in diameter. The risk is higher with polyps > 1 cm, but it also depends on the type of polyp. Some polyps even 5 cm or bigger have no cancer. On the other hand, I have seen 1 cm polyps with cancer. Bottom line: if the polyp found is < 1 cm in diameter, then it almost certainly will not have cancer.
Only 5 % of polyps progress to cancer, however, the individual risk for every person varies with the risk factor associated with that person. For instance, if one has a strong history of cancer in the family, the chances of this polyp progressing to cancer will be higher than those people without a family history of cancer. Other risk factors include smoking, fatty diet, inflammatory intestinal conditions, and inherited syndromes such FAP (familial adenomatous polyposis), DIABETES, OBESITY, ETC.
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Depending on gender, ethnicity and family history, about 10 to 30 percent.