Women's Health

Taurine Reduces the Risk of Coronary Heart Disease in Women

Taurine Reduces the Risk of Coronary Heart Disease in Women

Taurine protects against coronary heart disease in women having with high cholesterol which is not so common. According to the European Journal of Nutrition it is revealed that taurine – the amino acid found in high amounts in poultry meat and also in other food products is highly useful and works as a  protective element against heart disease mainly in women having higher cholesterol level. Taurine is always a part of blood pressure regulation, variety of antioxidant and anti-inflammatory properties. The studies regarding the Taurine also uncovered lot many heart benefits which are mainly caused for the amino acid in animals. The current study about the relevant topic is the first prospective study of taurine and the risks involved in the humans about heart disease.

A new study published in the European Journal of Nutrition report that taurine, an amino acid, may reduce the risk of heart diseases. According to researcher Yu Chen, PhD, MPH, associate professor of epidemiology at the NYU Langone Medical Center in New York, the risk of coronary heart disease reduces considerably by having good amounts of taurine in the diet. This is especially true of women who have high levels of cholesterol in blood. The research was focussed on the effect of taurine in women, but Chen hopes that the same benefits may be seen in men as well.

Taurine is mainly found in dark turkey and chicken meat, and seafood, like white fish, mussels, and clams. It is also found in some energy drinks that are used to improve the athletic performance. Taurine found in energy drinks is man-made, and the total content in the drink is unknown. In this study, only natural source of taurine was taken into consideration. Preliminary animal studies on this amino acid have shown that taurine is involved in the regulation of blood pressure and is also found to have antioxidant properties.

Data for the study, blood sample analysis and dietary details, was collected from the NYU Women's Health Study, which recruited more than 14,000 women between the ages of 34-years-old and 65-years-old. The blood sample and the diet of 223 women who developed heart disease during the study were compared with that of 223 women who did not develop any heart problems. The participants were divided into three groups based on the level of taurine in the blood.

When the group with highest levels of taurine was compared to those having low levels of this amino acid, the reduction in the risk of heart disease was not substantial. In women who had high levels of total cholesterol in blood (over 250 mg/dL) the lowest risk of heart disease was found in those who had high levels of taurine in the blood. Women who had high cholesterol levels having high amounts of taurine in blood had a 60% reduction in the risk of coronary heart disease. Researchers were not sure what foods should be taken to have such high levels of taurine.

It is not known how taurine is linked to lowered risk of heart diseases. According to Chen, it should be due to the anti-inflammatory and antioxidant properties of taurine. “Those with high cholesterol levels can be recommended with a modified diet in addition to the medications," adds Chen.

NYU Women's Health Study

According to New York University (NYU) School of Medicine where the study has been conducted   by the professors and the other experts who have analysed the data and have made detailed study about Women's Health. The entire study involved over 14,000 women between the ages of 34 to 65 from 1985 to 1991. The doctors have measured the level of taurine in two prediagnostic serum samples from 223 participants who developed coronary heart disease and 223 women who had no history of the disease over the study's twenty year follow up period.

Women having high intake of saturated fat are intended to have a lower intake of taurine. Although there was no relationship found between taurine and coronary heart disease during the entire survey among the women. Some of the women with high cholesterol which is greater than 250 milligrams per deciliter were analysed. It has shown unexpected results for the in terms of  Hypercholesterolemic women having intake of taurine which was top and about one-third of the women  had a 64 percent lower risk of heart disease which is compared with the women having lower third. According to the researchers, the information also offers a protective effect for taurine against the risk of high blood pressure and diabetes. If the findings are simulated, additional taurine or enlarged taurine intake from food might be suggested for women with elevated cholesterol, who are at the higher risk of having cardiovascular disease.

"Our findings were very interesting," commented Dr Chen. "Taurine, at least in its natural form, does seem to have a significant protective effect in women with high cholesterol."

Women having cardiovascular disease

American Cancer Society and Tufts University researchers evaluated data from 38,180 men and 60,289 women who had no history of heart disease upon enrolment in the Cancer Prevention Study II Nutrition in 1999. Dietary questionnaire responses were analysed for the intake of seven classes of flavonoids, including flavan-3-ols, flavanones, flavones, flavonols, isoflavones, anthocyanidins and proanthocyanidins from a variety of plant foods. The subjects were followed for seven years, during which 1,589 men and 1,182 women died from cardiovascular disease.

Subjects whose total flavonoid intake was among the top one-fifth of participants had an 18 percent lower risk of dying from cardiovascular disease compared to those whose intake was among the lowest fifth. Among classes of flavonoids, increased intake of flavon-3-ols, flavones, flavonols, anthocyanidins and proanthocyanidins were associated with a reduction in the risk of fatal cardiovascular disease. For men, the protective effect of increased total flavonoids was greater for stroke than for heart disease.

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 Biotin water-soluble vitamin

Biotin is an unnumbered member of the B-complex family, normally only required in minute amounts. Biotin, a water-soluble vitamin, is used as a cofactor of enzymes involved in fatty acid metabolism, gluconeogenesis, and amino acid catabolism, making biotin essential in maintaining metabolic homeostasis. Biotin plays an important role in metabolic functioning as a coenzyme carrier of activated carbon dioxide in the TCA cycle (also known as the Krebs cycle). In its coenzyme form, biotin synthesizes glucose from non-carbohydrate sources, and synthesizes and breaks down certain fatty acids and amino acids.

It fuels Red Bull, 5-Hour Energy and Rockstar to improve performance, but taurine may also help prevent heart disease.

This is not the controversial synthetic taurine used in popular energy drinks, however, but the nutrient found naturally in dark meat of poultry and some shellfish and mollusks, such as shrimp, clams and oysters.

Taurine may provide protection against coronary heart disease in women with high cholesterol, researchers at New York University have found.

Eating foods with taurine may help to regulate blood pressure, protect against diabetes and reduce inflammation, according to researchers.

"There hasn't been a lot of research about taurine, mostly just animal studies, so we don't know a lot about it," said Dr. Yu Chen, an associate professor of epidemiology at NYU School of Medicine and principal researcher for the study.

The study used data and samples from the NYU Women's Health Study, and followed 446 participants between 1985 and 2006. It allowed researchers to measure taurine levels in blood samples before and after heart disease occurrence.

Researchers found that women with both high cholesterol and high levels of taurine in their blood were 60 percent less likely to develop or die from coronary heart disease than women with lower taurine levels.

Due to poor diet, lack of exercise or high blood pressure, arteries surrounding the heart can become clogged with materials such as plaque or cholesterol.

Since the majority of coronary heart disease is attributed to high cholesterol in the blood, and because most of this cholesterol comes from diet, Greenland said, people have been looking for non-drug approaches to treatment.

A heart-healthy diet includes:

• Meal plan low in saturated fat, cholesterol and sodium

• Sodium levels under 2300 milligrams/day for most people

• Sodium levels under 1500 milligrams/day for people who are 51 or older, have diabetes, high blood pressure, kidney disease and/or are African American

• Balanced diet that includes food from all five food groups

• Recommended diets: Mediterranean or DASH diet

• Mediterranean diet emphasizes healthy fats, fruits, vegetables and whole grains. Olive oil is the primary source of fat, fish is preferred over red meat and a moderate amount of wine is encouraged.

• DASH diet, ranked best overall diet of 2012, emphasizes fruits, vegetables, whole grains, fish, poultry, low-fat dairy products, nuts and legumes.