9. Fertility drugs
Fertility drugs increase the amount of estrogen in the body. There are a lot of opposing viewpoints on fertility drugs. Experts do agree that when women take them and do not conceive a child they have a greater risk than if they took them, became pregnant and had a child.
Early studies in the 1990’s suggested that there was an increased risk. Some experts were skeptical because there are so many other potential variables and possible overlapping risk factors, that the data could be inaccurate. Infertility itself is a risk of ovarian cancer.
According to the American Cancer Society, some studies using the fertility drug clomiphene citrate (Clomid) showed an increased risk. The risk was of the ovarian cancer type “low malignant potential.”
A study in 2015 including 250,000 British women showed that patients had 15 in 10,000 odds of being diagnosed with ovarian cancer when using In Vitro Fertilization Treatments. The American Society for Reproductive Medicine (ASRM) said the risk is small compared to women who received no treatment.
The drugs stimulate ovulation and create an atmosphere of high gonadotropin. A theory is that this process and result contributes to DNA damage. Scientists are studying the possible connection.