Exercise and Breast Cancer in Women

To gather their conclusions on the effect of exercise in the growth of breast tumor cells, and what mechanism was involved, the Danish team imbedded human breast cancer cells into laboratory mice. As a control, tumor cells were also placed in test tubes.

Blood serum samples were obtained from both healthy women and from those with breast cancer. The samples used to infuse tumor cells were taken both before and after exercise.

Their findings showed that:

• Serum samples taken after exercise reduced the ability of tumor cells to grow in test tubes or in mice. 
• Only 45 percent of mice with tumors steeped in post-exercise serum developed tumors, compared with 90 percent of mice with tumors not exposed to post-exercise serum or exposed to pre-exercise serum.
• There was a connection between exercise and a 50% reduction in the growth of cancer cells
• Serum samples taken after exercise reduced the ability of tumor cells to grow in test tubes or in mice.

The study results proved the presence of anti-tumor activity related to the Hippo pathway which aided in the suppression of tumor development.

It is further noted that this effect emerged only with serum samples taken after 15 minutes of moderate - to high-intensity exercise, according to the report in Cancer Research.