Women's Health

New MRI Contrast Agent Can Tell Aggressive Breast Cancer From Other Types

ER-positive cancers are the most common

ER-positive cancers are the most common breast cancers. ER-positive cancers have receptors for estrogen and so are fueled by that hormone; they grow in response to the presence of estrogen.

This sounds scary because there can be lots of estrogen throughout the body. But this means that the cancer responds readily to hormone therapy, which can help prevent the return of the cancer.

ER-positive cancers still produce EDB-FN, which attracts Gd3N@C80. So the images produced by the MRI will show highlights around the breast cancer tumor.

The idea was that, because more aggressive breast cancers produce more EDB-FN, the ZD2 will attach more gadolinium to the tumors, which will cause them to show more brightly on the MRI than less aggressive cancers.

Did that hold true?