Dr. Bruce Colston Trapnell M.D.
Pulmonologist | Pulmonary Disease
222 Piedmont Ave Suite 6000 Cincinnati OH, 45219About
Bruce Trapnell, MS, MD received his medical degree from the University of Maryland in 1985, and completed a medical residency at The Ohio State University Hospitals and a fellowship in pulmonary medic ...
Education and Training
Univ of Md Sch of Med, Baltimore Md 1984
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Internalization of adenovirus by alveolar macrophages initiates early proinflammatory signaling during acute respiratory tract infection.
- GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.
- Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema.
- Granulocyte macrophage-colony stimulating factor augmentation therapy in sepsis: is there a role?
- GM-CSF, via PU.1, regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma -mediated molecular connection between innate and adaptive immunity in the lung.
- Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1.
- Genetic disorders influencing lung formation and function at birth.
- GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS.
- PU.1 redirects adenovirus to lysosomes in alveolar macrophages, uncoupling internalization from infection.
- GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.
- Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review.
- Anti-cytokine autoantibodies are ubiquitous in healthy individuals.
- Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan.
- Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.
- Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects.
Treatments
- Cystic Fibrosis (cf), Alpha-1 Antitrypsin Deficiency, Lung Problems And More
Fellowships
- National Heart, Lung & Blood Institute - Bethesda, MD
- Pulmonary Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 1989
Dr. Bruce Colston Trapnell M.D.'s Practice location
Practice At 222 Piedmont Ave Suite 6000
222 Piedmont Ave Suite 6000 -Cincinnati, OH 45219Get Direction
Dr. Bruce Colston Trapnell M.D.'s reviews
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Pneumonia in an Immunocompromised PatientPneumonia as a disease was once dreaded, since most of the cases would turn out to be fatal. This was many years ago, and with medical advances, times have changed. However, in some severe cases of pneumonia, especially in people with weakened immune systems, the disease can still be fatal. If the...
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Radiologists Look for Patterns in Cystic Fibrosis as More Adults Are DiagnosedRecent research shows that there is an increasing number of adults being diagnosed with cystic fibrosis. This information is leading scientists to believe cystic fibrosis is now just as much of an adult condition as a childhood condition. This increase has caused scientists and radiologists to...
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