Dr. Frank Rhame, MD

Expert Publications

• Implications of "market baskets," a pharmaceutical marketing practice.
• Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir.
• Quantifying and documenting prior beliefs in clinical trials.
• Nationwide epidemic of septicemia caused by contaminated intravenous products: mechanisms of intrinsic contamination.
• Uncertain generalizability of switch studies.
• Nationwide epidemic of septicemia caused by contaminated intravenous products. I. Epidemiologic and clinical features.
• Preventing HIV transmission. Strategies to protect clinicians and patients.
• Prevention of nosocomial aspergillosis.
• Increasing CD8+ T lymphocytes predict subsequent development of intraoral lesions among individuals in the early stages of infection by the human immunodeficiency virus.
• Effect of oral dextran sulfate on the mouse intestinal tract.
• The epidemiology of classic, African, and immunosuppressed Kaposi's sarcoma.
• Human immunodeficiency virus infection in patients with solid-organ transplants: report of five cases and review.
• Determination of the underlying cause of death in three multicenter international HIV clinical trials.
• An open-label, dose-ranging trial of AL 721 in patients with persistent generalized lymphadenopathy and AIDS-related complex.
• A look-back investigation of patients of an HIV-infected physician. Public health implications.

Media Releases

Get to know Infectious Disease Specialist, Dr. Frank Rhame, who serves patients in Minneapolis, Minnesota. 

Specializing in travel medicine, Dr. Rhame is a fellowship-trained infectious disease specialist at Allina Health Uptown Clinic in Minneapolis, Minnesota. His professional interests include HIV infections, hepatitis B, hepatitis C, transgender care, post-adolescent gender affirming hormones, pre-exposure HIV prophylaxis, infectious diseases research, inpatient and outpatient infectious disease, LGBTQ health, and virtual visits.

As for his academic appointments, he serves as an Adjunct Professor of the Infectious Diseases Section within the Department of Medicine at the University of Minnesota Medical School, and as an Adjunct Associate Professor within the Division of Epidemiology and Community Health at the University of Minnesota School of Public Health.

With a broad educational background, Dr. Rhame graduated with his medical degree from Columbia University Vagelos College of Physicians and Surgeons in 1968. He then went on to perform his internship at Harlem Hospital Center, followed by his residency and fellowship in infectious disease at Stanford University Hospital. 

With nearly five decades of experience, he is board-certified in internal medicine and infectious disease by the American Board of Internal Medicine (ABIM). The ABIM is a physician-led, non-profit, independent evaluation organization driven by doctors who want to achieve higher standards for better care in a rapidly changing world.

When HIV arose, Dr. Rhame returned to his first love: virology. Since then, his clinical, research, and educational focus has been on HIV, hepatitis C, influenza, Zika virus, and respiratory syncytial virus. He treats general infectious diseases in the clinic and inpatient consultation at Abbott Northwestern Hospital.

During 2018, he received payments from Gilead Sciences ($19,940), ViiV Healthcare ($10,760), Simply Speaking ($3,150), and the University of Minnesota ($850) for attending four speaker training meetings, attending three webinars, participating in three advisory boards, and delivering nine lectures.

Infectious disease is a medical specialty dealing with prevention, the diagnosis, and treatment of infections. Infectious disease specialists provide long-term care to people with diseases that are lifelong or last for more than one year. They employ a variety of antimicrobial agents to help treat infections.

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