Dr. Ellis D Avner MD
Nephrologist (Pediatric) | Pediatric NephrologyChildren's Hospital Of Wisconsin 9000 West Wisconsin Milwaukee WI, 53226
Ellis D. Avner, MD, was appointed Founding Director of the Children's Research Institute and Associate Dean for Pediatric Research in 2004. He currently serves as Professor of Pediatrics and Physiolog ...
DermatologyAmerican Board of DermatologyABD
- Pediatric renal transplantation: indications and special considerations. A position paper from the Pediatric Committee of the American Society of Transplant Physicians.
- New insights into the molecular pathophysiology of polycystic kidney disease.
- In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor.
- Glomerulosclerosis and hypoplasia--a common theme?
- Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor.
- Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease.
- Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene.
- Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease.
- Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice.
- Role of CFTR in autosomal recessive polycystic kidney disease.
- Childhood ADPKD: answers and more questions.
- Expression of the orpk disease gene during kidney development and maturation.
- Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented?
- A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease.
- Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD.
- Critical choices in mentoring the next generation of academic pediatricians: nine circles of hell or salvation?
- Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability.
- Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease.
- EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
- Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease.
- EGF-related growth factors in the pathogenesis of murine ARPKD.
- The case against screening urinalyses for asymptomatic bacteriuria in children.
- Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats.
- Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease.
- Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD).
- Renal cystic disease: new insights for the clinician.
- Inherited polycystic kidney disease in children.
- Src inhibition ameliorates polycystic kidney disease.
- 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease.
- Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD.
- 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.
- Localization of arginine biosynthetic enzymes in renal proximal tubules and abundance of mRNA during development.
- Diagnosis and management of childhood polycystic kidney disease.
- Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents.
- Polypeptide growth factors and the kidney: a developmental perspective.
- Polypeptide growth factors in metanephric growth and segmental nephron differentiation.
- Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease".
- Role of genetic modifiers in an orthologous rat model of ARPKD.
- HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.
- G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.
- New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications.
- Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.
- Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts.
- Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy.
- Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver.
- In vitro modulation of tubular cyst regression in murine polycystic kidney disease.
- Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity.
- Emerging Therapies for Childhood Polycystic Kidney Disease.
- Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation.
- Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease.
- Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.
- Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells.
- Sodium-potassium ATPase activity mediates cyst formation in metanephric organ culture.
- Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.
- Silica and glomerulonephritis: case report and review of the literature.
- Renal epithelial development in organotypic culture.
- Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation.
- Renal cystic disease. Insights from recent experimental investigations.
- Renal failure in children with hepatic failure undergoing liver transplantation.
- Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation.
- Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors.
- Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney.
- Growth factor requirements of organogenesis in serum-free metanephric organ culture.
- Regression of genetically determined polycystic kidney disease in murine organ culture.
- Effects of improved glycemic control on microalbuminuria in adolescents with insulin-dependent diabetes mellitus.
- Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II).
- Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture.
- A new model of glucocorticoid-induced metanephric maldevelopment.
- Veno-occlusive disease of the liver associated with cysteamine treatment of nephropathic cystinosis.
- Metanephric development in serum-free organ culture.
- Neonatal radiocontrast nephropathy simulating infantile polycystic kidney disease.
- Cystic maldevelopment of the kidney.
- 1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development.
- Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis.
- Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor.
- Clinical disorders of water metabolism: hyponatremia and hypernatremia.
- Epidermal growth factor receptor expression is abnormal in murine polycystic kidney.
- Renal transplantation and chronic dialysis in children and adolescents: the 1993
- Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture.
- Hypercalciuria and nephrocalcinosis in the oculocerebrorenal syndrome.
- Gene time for polycystic kidney disease.
- Escherichia coli O 157:H7-associated hemolytic-uremic syndrome after ingestion of contaminated hamburgers.
- Epithelial polarity and differentiation in polycystic kidney disease.
- Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.
- Renal developmental diseases.
- A new murine model of autosomal recessive polycystic kidney disease.
- Normal and abnormal nephrogenesis.
- Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease.
- Congenital nephropathies and uropathies.
- Clinical quiz. Differential diagnosis of a patient with hypertension.
- Clinical quiz. Differential diagnosis of a patient with Wegener's granulomatosis.
- Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response
- Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic.
- Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.
- Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion.
- Improved outcome of young children on nightly automated peritoneal dialysis.
- Efficacy of taxol in the orpk mouse model of polycystic kidney disease.
- Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.
- The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development.
- Pediatric renal biopsy: should this procedure be performed in an outpatient setting?
- Cell and molecular biology of kidney development.
- Cholelithiasis following Escherichia coli O157:H7-associated hemolytic uremic syndrome.
- Functional genomics in the post-genome era.
- Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease.
- Morphological and functional characterization of a conditionally immortalized collecting tubule cell line.
- PKD and CF: an interesting family provides insight into the molecular pathophysiology of polycystic kidney disease.
- The molecular biology of polycystic kidney disease.
- Princeton University 1970 Magna cum Laude
- 1970 Woodrow Wilson National Scholar
- 1974 Alpha Omega Alpha Honor Medical Society
- Spencer Morris Prize in Medicine, 1975 University of Pennsylvania School of Medicine
- March of Dimes National Birth Defects Foundation Basil O'Connor Research Award
- National Institutes of Health New Investigator Research Award
- Award of Tenure, 1986 University of Pittsburgh School of Medicine
- Award of Tenure, 1990 University of Washington School of Medicine
- Institute of Child Health, London, England 1994 Kidney Research Aid Fund Award
- 1994 Best Doctors in America, Woodward/White, Inc.
- 1995 Mitchell Rubin Award in Pediatric Nephrology, Children's Hospital of
- Case Western Reserve University School of Medicine 1995 Award of Tenure
- 1996 David Cornfeld Award in Pediatric Nephrology, Children's Hospital of
- American Association for the Advancement of Science For outstanding co 1997 Elected Fellow
- Wayne State University School of Medicine 1997 Dean's Distinguished Lecturer
- 2001 The Jean Pouliot Award and Lectureship in Pediatric Research, Montrea
- Royal National Lao University, Lao PDR 2001 Distinguished Service Award in Health Care Education
- Million Dollar Professor
- 2002 March of Dimes Distinguished Lecturer, New York Academy of Medicine
- Lifetime Achievement Award, Strathmore's Who's Who Honored Member
- 2003 Howard Mermelstein Memorial Lecture, Children's Hospital of Pittsburg
- 2004 Award of Tenure, Medical College of Wisconsin
- 2008 Henry L. Barnett Award for Excellence in Clinical Care and Education
- 2010 MCW's Outstanding Medical Student Teacher (Physiology)
- 2012 Named: America's Top Pediatricians, Consumers Research Council of Ame
- 2013 Named: Leading Physicians in the World (IAHCP)
- Polycystic Kidney Disease, Kidney Problems
- Children's Hospital Boston 1975
- Boston Children's Hospital - Ped Nephrology 1980
- Pediatric Nephrology - Children's Hospital - Boston, MA 1978
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- Wilms Tumor Facts
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- What Is Renal Ultrasound Used For?
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- Nephrotic Syndrome in Children: What You Need to Know
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- What Could Lead to Nephrotic Syndrome?
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