Dr. Jean Schaffer is a cardiologist practicing in Saint Louis, MO. Dr. Schaffer specializes in diagnosing, monitoring, and treating diseases or conditions of the heart and blood vessels and the cardiovascular system. These conditions include heart attacks, heart murmurs, coronary heart disease, and hypertension. Dr. Schaffer also practices preventative medicine, helping patients maintain a heart-healthy life.
Education and Training
Harvard Med Sch, Boston Ma 1986
Internal MedicineAmerican Board of Internal MedicineABIM
- Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane.
- Molecular aspects of fatty acid transport: mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function.
- Palmitate-induced apoptosis can occur through a ceramide-independent pathway.
- A novel mouse model of lipotoxic cardiomyopathy.
- Membrane topology of the murine fatty acid transport protein 1.
- Fatty acid transport: the roads taken.
- FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation.
- Mechanisms of lipoapoptosis: implications for human heart disease.
- Oligomerization of the murine fatty acid transport protein 1.
- Triglyceride accumulation protects against fatty acid-induced lipotoxicity.
- Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development.
- Lipotoxicity: when tissues overeat.
- cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells.
- Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy.
- A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death.
- Beth Israel Deaconess Hp M C, Cardiovascular Diseases; Brigham & Women'S Hosp, Internal Medicine
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