Dr. Colin Klaus Franz M.D. PH.D.
Physiatrist (Physical Medicine) | Physical Medicine & Rehabilitation
355 E. Erie St. 15 floor Chicago IL, 60611About
About Me
Dr. Colin Franz, MD/PhD, is a physician and scientist at the Shirley Ryan AbilityLab. His subspecialties include neuromuscular medicine, electrodiagnostic medicine, and neuromuscular ultrasound. He see patients for (i) peripheral nerve injuries, (ii) brachial plexus injuries, (iii) nerve or tendon transfer candidates or postoperative rehabilitation, (iv) polyneuropathy, diaphragm muscle weakness and ultrasound studies, and (v) motor neuron diseases such as ALS. He is the director of the Electromyography (clinical) and Regenerative Neurorehabilitation (research) laboratories at the Shirley Ryan AbilityLab hospital.
His research is heavily inspired by the patient populations he cares for. His laboratory team takes a highly technology-oriented approach to precision rehabilitation medicine. Current studies range from transient (resorbable) implanted devices to deliver therapeutics directly to regenerating axons, to making human neurons derived from patient-derived pluripotent stem cells to determine isolate how individual genetic factors effect neurotrauma outcomes. Via many strong collaborations in Chicago and across North America, his lab is able to address clinical problems in neurorehabilitation, neurotrauma, nerve regeneration and degeneration. His research is supported by the NIH, Craig H. Nielsen Foundation, Foundation for Physical Medicine and Rehabilitation, as well as private gifts from community members such as the Belle Carnell (in memoriam) Regeneration Neurorehabilitation Fund.
Education and Training
Dalhousie University PhD 2007
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Polysialylated neural cell adhesion molecule is necessary for selective targeting of regenerating motor neurons.
- Intrinsic neuronal properties control selective targeting of regenerating motoneurons.
- Neural cell adhesion molecule is required for stability of reinnervated neuromuscular junctions.
- Accelerated axon outgrowth, guidance, and target reinnervation across nerve
- Brief transvertebral electrical stimulation of the spinal cord improves the specificity of femoral nerve reinnervation.
- Regulated neuronal neuromodulation via spinal cord expression of the gene for the inwardly rectifying potassium channel 2.1 (Kir2.1).
- Central Adaptation following Brachial Plexus Injury.
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