Dr. Leonard Hillel Lazarus M.D.
Internist
6515 La Jolla Blvd La Jolla CA, 92037About
Dr. Leonard Lazarus is an internist practicing in La Jolla, CA. Dr. Lazarus specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Lazarus provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Education and Training
Univ Of Cape Town- Fac Of Med- Cape Town- So Africa 1977
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Opioid deltorphin C analogues containing cis- or trans-2- or 3- or 4-aminocyclohexanecarboxylic acid residues.
- What peptides these deltorphins be.
- Synthesis of pyrazinone ring-containing opioid mimetics and examination of their opioid receptor-binding activity.
- Further studies on the Dmt-Tic pharmacophore: hydrophobic substituents at the C-terminus endow delta antagonists to manifest mu agonism or mu antagonism.
- beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.
- Characterization of N,N(Me)2-Dmt-Tic-OH, a delta selective opioid dipeptide antagonist.
- Synthesis of stereoisomeric analogues of endomorphin-2, H-Tyr-Pro-Phe-Phe-NH(2), and examination of their opioid receptor binding activities and solution conformation.
- Inverse agonism by Dmt-Tic analogues and HS 378, a naltrindole analogue.
- Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
- Assessment of substitution in the second pharmacophore of Dmt-Tic analogues.
- Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist.
- Fluctuation in activity of the molecular forms of cellular DNA polymerase during infection by SV40.
- Fluctuation in activity of the molecular forms of cellular DNA polymerase during infection by SV40.
- Stereospecificity of amino acid side chains in deltorphin defines binding to opioid receptors.
- Para-substituted Phe3 deltorphin analogues: enhanced selectivity of halogenated derivatives for delta opioid receptor sites.
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