Dr. Katherine A High MD
Hematologist (Pediatric) | Pediatric Hematology-Oncology
34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104About
Dr. Katherine High is a pediatric hematologist practicing in Philadelphia, PA. Dr. High specializes in treating children that have a blood disease or cancer. Such blood diseases include disorders of red blood cells, white blood cells and/or platelets. The types of cancers that Dr. High treats include leukemias, lymphomas and certain tumors. Dr. High can also treat bleeding disorders in children. Pediatric hematologists can be found in childrens hospitals, community hospitals, university medical centers and more.
Education and Training
Physician Assistant Studies, Barry University, FL 1978
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Hematology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapy.
- A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates.
- Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy.
- Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.
- Factor VII mutant V154G models a zymogen-like form of factor VIIa.
- Adeno-associated virus-mediated gene transfer for hemophilia B.
- AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.
- Gene transfer as an approach to treating hemophilia.
- Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.
- The risks of germline gene transfer.
- Homocysteine and prothrombin fragment 1+2 levels in patients with veno-occlusive
- Theodore E. Woodward Award. AAV-mediated gene transfer for hemophilia.
- Coaxing coagulation with RNA and cell fragments.
- Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.
- Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.
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