Dr. Elaine M. Majerus, MD, PhD

Expert Publications

• Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura.
• O-fucosylation is required for ADAMTS13 secretion.
• ADAMTS13 bound to endothelial cells exhibits enhanced cleavage of von Willebrand
• Multi-step binding of ADAMTS-13 to von Willebrand factor.

Clinical Trials

• Low Dose Rituximab in Thrombotic Thrombocytopenic Purpura

Media Releases

Get to know Hematologist Dr. Elaine M. Majerus, who serves patients in St. Louis, Missouri.

A skilled hematologist, Dr. Majerus is the Director of the Washington University Center for the Treatment of Bleeding and Blood Clotting Disorders. Her areas of clinical interest include hemophilia and bleeding disorders, thrombosis, paroxysmal nocturnal hemoglobinuria, and atypical hemolytic uremic syndrome.

The Washington University Center for the Treatment of Bleeding and Blood Clotting Disorders brings together experts from a range of specialties to provide comprehensive, integrated care to patients with bleeding, clotting, and other hematologic disorders in a federally supported center of excellence. The center has a specialty pharmacy and 340B Factor Program that patients may use for their home therapy and nursing needs. It also provides education on infusion and drug administration as part of one’s treatment plan.

Among her other academic and clinical appointments, Dr. Majerus holds an Interim Chief and Professor position at Washington University School of Medicine in St. Louis, Division of Hematology. She also sees patients at Center for Advanced Medicine Siteman Cancer Center, Center for Advanced Medicine – South County, Barnes-Jewish West County Hospital – Medical Building 2, Barnes-Jewish Hospital, and Boone Hospital. 

With a broad educational background, Dr. Majerus holds a Bachelor of Arts degree in Biology and a Doctorate degree in Molecular Cell Biology and Biochemistry from the Washington University. She earned her medical degree at St. Louis University in 1998 and went on to complete her internship and residency in internal medicine at Barnes-Jewish Hospital. Finally, she completed her fellowship in hematology-oncology at the Washington University School of Medicine in St. Louis in 2005. 

Licensed to practice medicine in Missouri and Illinois, the doctor is board-certified in internal medicine and hematology by the American Board of Internal Medicine (ABIM). The ABIM is a physician-led, non-profit, independent evaluation organization driven by doctors who want to achieve higher standards for better care in a rapidly changing world.

Advancing her efforts, Dr. Majerus is a member of the American Society of Hematology and the Hemostasis and Thrombosis Research Society.

“My research focus at this time is on improving treatment for bleeding disorders.

Hematology is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood.. A hematologist  is a physician who specializes in the diagnosis and  treatment of  blood disorders such as iron-deficiency anemia, clotting abnormalities, hemophilia, and sickle-cell disease.

As a testament to her success in the field, Dr. Majerus has accepted many awards and honors, including the Loretta Backer Scholarship, the Lucille P. Markey Research Fellow, the Alpha Omega Alpha Student Research Forum Prize, and the Physician-Scientist Training Program Fellow.

On a more personal note, she speaks  English and a little French.

Recommended Articles

• What are the Side Effects of Chemotherapy?

  Chemotherapy is a treatment method which makes use of certain drugs in treating cancer. It plays a number of roles in the body as part of the treatment mechanism. This may include killing cancer cells, reducing their rate of spreading or shrinking the tumors to reduce the recurrence and...

• The Different Stages of Bladder Cancer

  What Are the Different Stages of Bladder Cancer?When coming up with a suitable treatment process with a doctor, you begin by staging your disease. Staging bladder cancer is one of the most critical factors considered when making decisions on treatment options. Your health care providers use...

• Limit Your Risk for Prostate Cancer with Statins

  A recent study has shown that the levels of prostate specific antigen (PSA), a marker of prostate cancer, lower in men who take statin drugs. This may lower the risk of advanced prostate cancer in men, according to a study published in the Journal of the National Cancer Institute.High levels of PSA...

• The Effect of Insurance on Breast Cancer

  Early diagnosis is incredibly important in determining the chance of survival that someone with breast cancer will have. Screening and detection methods for breast cancer have made leaps and bounds over the years, but only for those people who have access to regular screening. Insurance plays a huge...

• Cancer Answers: Is There a Screening Test for Ovarian Cancer?

  Symptoms of ovarian cancer do not present themselves within early stages and in most cases, ovarian cancer is not detected during routine pelvic examinations.For this reason, most women with ovarian cancer are diagnosed at an advanced stage – stage III or stage IV – at which case the cancer...

• Ovarian Cancer Survivor Dedicates Herself to Helping Others

  July 11th, 2014 is a day LeToy Hannah will never forget. She had gone into surgery to remove a non-cancerous cyst on her ovary and came out with a stage 3C ovarian cancer diagnosis. Hannah was shocked; her mother had to make the call to do a complete hysterectomy to remove all visible cancer while...