Dr. Roy Gerard is a nephrologist practicing in Tyler, TX. Dr. Gerard specializes in the care and treatment of the kidneys. As a nephrologist, Dr. Gerard most typically treats conditions like kidney stones, chronic kidney disease, acute renal failure, polycystuc kidney disease, high blood pressure and more. Nephrologists are also experts on kidney transplantation and dialysis. They are usually referred to by primary care physicians for problems related to the kidneys, and while they can perform tests to diagnose kidney disorders, they do not perform surgeries.
- Percutaneous adenoviral gene transfer into porcine coronary arteries: is catheter-based gene delivery adapted to coronary circulation?
- Storage of tissue-type plasminogen activator in Weibel-Palade bodies of human endothelial cells.
- Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors.
- Percutaneous gene therapy using recombinant adenoviruses encoding human herpes simplex virus thymidine kinase, human PAI-1, and human NOS3 in balloon-injured porcine coronary arteries.
- Tissue-specific androgen responses in primary cultures of lacrimal epithelial cells studied by adenoviral gene transfer.
- Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism.
- The end of the beginning. Gene transfer into the vessel wall.
- Condensation of atmospheric moisture from tropical maritime air masses as a freshwater resource.
- Desalination of cold seawater.
- Anomalous bottom water South of the grand banks suggests turbidity current activity.
- Anomalous water in the deep ocean suggests lateral advection-stirring.
- Wine-making: an eternal art.
- Preliminary X-ray analysis of crystals of plasminogen activator inhibitor-1.
- Adenoviral targeting of gene expression to tumors.
- Deacylated lipopolysaccharide inhibits plasminogen activator inhibitor-1, prostacyclin, and prostaglandin E2 induction by lipopolysaccharide but not by tumor necrosis factor-alpha.
- Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1.
- Retargeting adenoviral vectors to improve gene transfer into tumors.
- Mutational and immunochemical analysis of plasminogen activator inhibitor 1.
- Restoration of serine protease-inhibitor interaction by protein engineering.
- MicroRNA silencing improves the tumor specificity of adenoviral transgene expression.
- Peptide targeting of adenoviral vectors to augment tumor gene transfer.
- Expression of human plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli as a soluble protein comprised of active and latent forms. Isolation and crystallization of latent PAI-1.
- Serpin-resistant mutants of human tissue-type plasminogen activator.
- Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen.
- Elevated levels of creatine kinase BB isoenzyme in three patients with adult osteopetrosis.
- T antigen and template requirements for SV40 DNA replication in vitro.
- New host cell system for regulated simian virus 40 DNA replication.
- Analysis of nonpermissivity in mouse cells overexpressing simian virus 40 T antigen.
- Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen.
- Potential freshwater reservoir in the New York area.
- Deletion mutants which affect the nuclease-sensitive site in simian virus 40 chromatin.
- Structure of the receptor binding domain of adenovirus type 5 fiber protein.
- Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition.
- Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution.
- Adenovirus-mediated delivery into myocytes of muscle glycogen phosphorylase, the enzyme deficient in patients with glycogen-storage disease type V.
- Use of recombinant adenovirus for metabolic engineering of mammalian cells.
- Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli.
- The adenovirus-mediated delivery of a reporter gene permits the assessment of androgen receptor function in genital skin fibroblast cultures. Stimulation of Gs and inhibition of G(o).
- Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
- Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice.
- Characterization of a plasminogen activator produced by Acanthamoeba castellanii.
- Sequence requirements in the reactive-center loop of plasminogen-activator inhibitor-1 for recognition of plasminogen activators.
- Adenovirus-mediated gene transfer: strategies and applications in lipoprotein research.
- Adenoviral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats.
- Systemic hypertension induced by hepatic overexpression of human preproendothelin-1 in rats.
- Adenovirus-mediated transfer of tissue-type plasminogen activator augments thrombolysis in tissue-type plasminogen activator-deficient and plasminogen activator inhibitor-1-overexpressing mice.
- Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing
- Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis.
- Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.
- Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs.
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