Dr. Douglas T Golenbock M.D.
Infectious Disease Specialist | Infectious Disease
55 Lake Ave N Department Of Infect Worcester MA, 01655About
Dr. Douglas Golenbock is an infectious disease specialist practicing in Worcester, MA. Dr. Golenbock specializes in infections that are difficult to diagnose or unresponsive to treatments, such as HIV or airborne infections from a foreign country. Infectious disease specialists usually work with conditions that are not treatable by a primary physician but it is important to keep contact with the primary physician in order to receive information about the patients history and for deciding which diagnostic tests are appropriate.
Education and Training
Univ of Mi Med Sch, Ann Arbor Mi 1980
University of Mi Med Sch 1980
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Internal MedicineAmerican Board of Internal MedicineABIM- Infectious Disease
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.
- Membrane expression of soluble endotoxin-binding proteins permits lipopolysaccharide signaling in Chinese hamster ovary fibroblasts independently of CD14.
- Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.
- Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression.
- Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411.
- Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis.
- Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
- The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.
- Characterization of low-density lipoprotein uptake by murine macrophages exposed to Chlamydia pneumoniae.
- Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
- Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.
- The biology of Toll-like receptors.
- A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/toll-like receptor 4 signaling pathway.
- Divergent response to LPS and bacteria in CD14-deficient murine macrophages.
- Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Awards
- Squibb Award / National Foundation for Infectious Dis. 1986
- NIH Physician Scientist Award 1987
- American Cancer Society Junior Faculty Award 1994
- American Society for Clinical Investigation 1997
- Awarded Tenure, 2003
- Inducted to Association of American Physicians 2007
- Awarded NIH Merit Award (GM54060) 2008
- Forsythe Dental Inst Scientific Advisory Board 2010
- Honor Chair ITS FUMG Belo Horisonte Brazil 2010
- ATCC/BIodefense & Emerg Infections Scientific Writing Group Leader 2011
Professional Memberships
- Member UMass Memorial Medical Group
Fellowships
- University of Wisconsin Hospitals and Clinics (Infectious Diseases)
- University of Wisconsin Hospital and Clinics, Fellow:Infectious Diseases 1984
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