
Dr. Jonathan Kost, MD
Pain Management Specialist | Interventional Pain Medicine
435 Lewis Ave., 100 Meriden CT, 06451About
Jonathan Kost, MD, is a highly respected interventional pain medicine specialist known for his expertise, innovation, and compassionate approach to patient care. As the Founder and Medical Director of the Spine and Pain Institute at MidState Medical Center and Founder of the Hartford Hospital Pain Treatment Center, he has dedicated his career to improving the lives of those suffering from chronic pain.
With over 30 years of experience in interventional and multidisciplinary pain management, Dr. Kost is board-certified in both Anesthesiology and Pain Medicine. He completed his interventional pain medicine fellowship at Harvard’s Brigham and Women’s Hospital and his anesthesiology residency at Beth Israel/Mount Sinai Hospitals in New York City.
A pioneer in the field, Dr. Kost established Connecticut’s only multidisciplinary pain treatment center and New England’s first EDS Society Center of Excellence for Pain Management. His expertise extends beyond clinical practice; he actively contributes to Connecticut’s Workers’ Compensation Commission and the Department of Consumer Protection’s state medical advisory boards. He also serves as an Associate Clinical Professor at both the UConn School of Medicine and the Frank H. Netter School of Medicine. Additionally, he has played a key leadership role in Hartford HealthCare’s Neuroscience Division for Opioid and Pain Councils and is a co-founder and past president of the Connecticut Pain Society.
Beyond his clinical and academic contributions, Dr. Kost is the visionary founder of Digital360Health, a groundbreaking medical software company that enhances patient-provider and provider-provider communication, interprets pharmacogenetic testing for drug metabolism and interactions, and transforms patient data collection to improve healthcare outcomes.
Dr. Kost is particularly committed to diagnosing and treating Hypermobile Ehlers-Danlos Syndrome (hEDS), one of the most underdiagnosed and undertreated conditions in medicine. A passionate advocate for greater awareness, he often tells audiences, “It is highly likely that you know someone with this condition—undiagnosed and suffering.” Through research, education, and clinical care, he strives to improve the recognition and treatment of hEDS, ensuring patients receive the compassionate support and specialized care they deserve.
Board Certification
American Board of Anesthesiology
Pain Medicine (Anesthesiology)
Provider Details

Dr. Jonathan Kost, MD's Expert Contributions
Hypermobile EDS; very likely you know someone who has it!
Hypermobile Ehlers-Danlos Syndrome (hEDS) is a complex and often misunderstood genetic disorder affecting connective tissues in the body. Despite its prevalence, many patients struggle to receive accurate diagnoses and appropriate treatment. This article aims to shed light on the specifics of hEDS,...
Areas of expertise and specialization
Faculty Titles & Positions
- Associate Clinical Professor UConn School of Medicine 2016 - Present
- Associate Clinical Professor Frank H. Netter School of Medicine 2018 - Present
Awards
- Center of excellence 2024 EDS Society
Internships
- Waterbury Hospital
Fellowships
- Brigham and Women\'s Hospital
Professional Society Memberships
- EDS society
What do you attribute your success to?
- curiosity and empathy
Areas of research
- Botulinum Toxin for the treatment of back pain
- CYP450 Genotyping and it's effect on drug metabolism
- Pharmacogenetics and the Personalization of Pain Management
- Genetically-Guided Pain Management with Opioids based on CYP2D6 and OPRM1 Polymorphisms
- Psychotropic and Pain Medication metabolism in Cytochrome P450 Genotyping
- Extraction of Pain Symptoms using a Natural Language AI Approach using Electronic Health Records.
- Sprint percutaneous PNS treatment for Sacroiliac (SI) joint lower back pain
- Sprint percutaneous PNS treatment for the treatment of chronic headaches
Dr. Jonathan Kost, MD's Practice location
Spine and Pain Institute at Midstate
435 Lewis Ave., 100 -Meriden, CT 06451Get Direction
Hartford Hospital Pain Treatment Center
65 Memorial Rd Suite 435 -West Hartford, CT 06107Get Direction
Dr. Jonathan Kost, MD's reviews
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Nearby Providers
- Dr. Annette Macannuco-Winslow M.D.65 Memorial Rd West Hartford CT 06107
- Dr. Dwight Paul Ligham MD1 Long Wharf Drive New Haven CT 06511
- Dr. Eric D Grahling MD440 New Britain Ave Plainville CT 06062
- Dr. Roshni Patel MD55 South Rd Farmington CT 06032
- Dr. Steven Carl Levin M.D.1 Long Wharf Dr New Haven CT 06511
- Dr. Lloyd Robert Saberski M.D.Advanced Diagnostic Pain Treatment Centers, Pc New Haven CT 06511
Nearest Hospitals
ST FRANCIS HOSPITAL & MEDICAL CENTERl
114 WOODLAND STREET HARTFORD CT 6105CONNECTICUT CHILDRENS MEDICAL CENTERl
282 WASHINGTON STREET HARTFORD CT 6106